C3AR1 Antibody (PACO15897)
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주문- SKU:
- PACO15897
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | C3AR1 Antibody (PACO15897) |
Antibody SKU: | PACO15897 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human C3AR1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO15897(C3AR1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO15897(C3AR1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The C3a receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptorprotein involved in the complement system. Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues. |
Synonyms: | complement component 3a receptor 1 |
UniProt Protein Function: | C3aR: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR Chromosomal Location of Human Ortholog: 12p13.31 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; C3a anaphylatoxin receptor activity; complement component C3a receptor activity; phosphoinositide phospholipase C activity Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; elevation of cytosolic calcium ion concentration; metabolic process; blood circulation; complement receptor mediated signaling pathway; chemotaxis; inflammatory response |
UniProt Code: | Q16581 |
NCBI GenInfo Identifier: | 37538305 |
NCBI Gene ID: | 719 |
NCBI Accession: | Q16581.2 |
UniProt Secondary Accession: | Q16581,O43771, Q92868, |
UniProt Related Accession: | Q16581 |
Molecular Weight: | 482 |
NCBI Full Name: | C3a anaphylatoxin chemotactic receptor |
NCBI Synonym Full Names: | complement component 3a receptor 1 |
NCBI Official Symbol: | C3AR1 |
NCBI Official Synonym Symbols: | AZ3B; C3AR; HNFAG09 |
NCBI Protein Information: | C3a anaphylatoxin chemotactic receptor; C3a-R; complement component 3 receptor 1 |
UniProt Protein Name: | C3a anaphylatoxin chemotactic receptor |
Protein Family: | C3a anaphylatoxin chemotactic receptor |
UniProt Gene Name: | C3AR1 |
UniProt Entry Name: | C3AR_HUMAN |
Antibodies | ELISA Kits |
Anti-C3AR1 Antibody (CAB6361) | Human C3a / Complement 3a ELISA Kit |
C3AR1 Antibody (PACO05252) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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