BLOC1S1 Antibody (PACO13383)
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주문- SKU:
- PACO13383
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | BLOC1S1 Antibody (PACO13383) |
Antibody SKU: | PACO13383 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human BLOC1S1-Specific |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | biogenesis of lysosomal organelles complex-1, subunit 1;BLOC1S1;BLOS1;FLJ39337;FLJ97089;GCN5L1;MGC87455;MICoA;RT14 ; |
UniProt Protein Function: | BLOC1S1: May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5A1 AND NDUFA9. May also be involved in the biogenesis of specialized organelles of the endosomal-lysosomal system. Belongs to the BLOC1S1 family. 2 isoforms of the human protein are produced by alternative initiation. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Vesicle Chromosomal Location of Human Ortholog: 12q13-q14 Cellular Component: extracellular space; lysosomal membrane; mitochondrial matrix; mitochondrial intermembrane space; cytosol Molecular Function:protein binding Biological Process: platelet dense granule organization and biogenesis; melanosome organization and biogenesis; anterograde synaptic vesicle transport; aerobic respiration; post-Golgi vesicle-mediated transport; anterograde axon cargo transport; peptidyl-lysine acetylation; neurite development |
NCBI Summary: | BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004 [PubMed 15102850]).[supplied by OMIM, Mar 2008] |
UniProt Code: | P78537 |
NCBI GenInfo Identifier: | 332278161 |
NCBI Gene ID: | 2647 |
NCBI Accession: | P78537.2 |
UniProt Secondary Accession: | P78537,Q6NZ45, A1L4Q9, |
UniProt Related Accession: | P78537 |
Molecular Weight: | 153 |
NCBI Full Name: | Biogenesis of lysosome-related organelles complex 1 subunit 1 |
NCBI Synonym Full Names: | biogenesis of lysosomal organelles complex-1, subunit 1 |
NCBI Official Symbol: | BLOC1S1 |
NCBI Official Synonym Symbols: | RT14; BLOS1; MICoA; GCN5L1 |
NCBI Protein Information: | biogenesis of lysosome-related organelles complex 1 subunit 1; BLOC subunit 1; BLOC-1 subunit 1; GCN5-like protein 1; MTA1-interacting coactivator; GCN5 general control of amino-acid synthesis 5-like 1; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1 |
UniProt Protein Name: | Biogenesis of lysosome-related organelles complex 1 subunit 1 |
UniProt Synonym Protein Names: | GCN5-like protein 1; Protein RT14 |
Protein Family: | Biogenesis of lysosome-related organelles complex |
UniProt Gene Name: | BLOC1S1 |
UniProt Entry Name: | BL1S1_HUMAN |