BCAT2 Antibody (PACO25220)
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주문- SKU:
- PACO25220
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | BCAT2 Antibody (PACO25220) |
Antibody SKU: | PACO25220 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Branched-chain-amino-acid, aminotransferase, mitochondrial protein (28-392AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: BCAT2 antibody at 2µg/ml Lane 1: NIH/3T3 whole cell lysate Lane 2: Mouse kidney tissue Lane 3: Mouse spleen tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 45, 34 kDa Observed band size: 45 kDa . |
![]() | Immunohistochemistry of paraffin-embedded human skin tissue using PACO25220 at dilution of 1:100. |
Background: | Catalyzes the first reaction in the catabolism of the essential branched chain amino acid, leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acid, . |
Synonyms: | Branched-chain-amino-acid, aminotransferase, mitochondrial (BCAT(m)) (EC 2.6.1.42) (Placental protein 18) (PP18), BCAT2, BCATM BCT2 ECA40 |
UniProt Protein Function: | BCAT2: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. Homodimer. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; EC 2.6.1.42; Mitochondrial; Transferase; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis Chromosomal Location of Human Ortholog: 19q13 Cellular Component: mitochondrion; mitochondrial matrix Molecular Function:branched-chain-amino-acid transaminase activity Biological Process: valine metabolic process; branched chain family amino acid catabolic process; leucine metabolic process; branched chain family amino acid biosynthetic process; isoleucine catabolic process |
NCBI Summary: | This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
UniProt Code: | O15382 |
NCBI GenInfo Identifier: | 20455470 |
NCBI Gene ID: | 587 |
NCBI Accession: | O15382.2 |
UniProt Secondary Accession: | O15382,O00269, Q96KG1, Q9BTB6, Q9BUU6, B2RB87, |
UniProt Related Accession: | O15382 |
Molecular Weight: | 33,777 Da |
NCBI Full Name: | Branched-chain-amino-acid aminotransferase, mitochondrial |
NCBI Synonym Full Names: | branched chain amino-acid transaminase 2, mitochondrial |
NCBI Official Symbol: | BCAT2 |
NCBI Official Synonym Symbols: | BCAM; BCT2; PP18; BCATM |
NCBI Protein Information: | branched-chain-amino-acid aminotransferase, mitochondrial; placental protein 18; branched chain aminotransferase 2, mitochondrial |
UniProt Protein Name: | Branched-chain-amino-acid aminotransferase, mitochondrial |
UniProt Synonym Protein Names: | Placental protein 18; PP18 |
UniProt Gene Name: | BCAT2 |
UniProt Entry Name: | BCAT2_HUMAN |