Batroxobin Recombinant Protein (RPPB2990)

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주문
SKU:
RPPB2990
Product type:
Recombinant Protein
Size:
50ug
Target:
Batroxobin
Synonyms:
Thrombin-like enzyme batroxobin
Synonyms:
EC 342174
Synonyms:
BX
Synonyms:
Bothrops atrox serine proteinase
Uniprot:
P04971
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Description

Product Name:Batroxobin Recombinant Protein
Product Code:RPPB2990
Size:50µg
Target:Batroxobin
Synonyms:Thrombin-like enzyme batroxobin, EC 3.4.21.74, BX, Bothrops atrox serine proteinase, Venombin-A, Defibrase, Reptilase, Batroxobin.
Physical Appearance:Sterile Filtered white lyophilized powder.
Formulation:The Batroxobin protein was lyophilized from a concentrated (1mg/ml) solution with no additives.
Solubility:It is recommended to reconstitute the lyophilized Batroxobin in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability:Batroxobin although stable at room temperature for 3 weeks, should be stored below -18°C. Upon reconstitution Batroxobin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
UniProt Code:P04971

Batroxobin is a serin protease that reduces fibronogen levels and is originally extracted from snake venom of Bothrops Atrox. Batroxobin is used in defibrinogenation and thrombolysis and also has an effect on c-fos gene and growth factor.Batroxobin can efficiently restrain proliferation of VSMCs, by blocking the release and uptake of Ca2+, thus influencing [Ca2+]i.Batroxobin converts fibrinogen to fibrin through the restricted release of fibrinopeptide-A from fibrinogen to promote blood to clot. Unlike thrombin, it is not affected by heparin and hirudin.

Batroxobin, isolated from Bothrops atrox snake venom, has an Mw of approximately 43kDa.

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