ATP6V1D Antibody (PACO63539)
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주문- SKU:
- PACO63539
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ATP6V1D Antibody (PACO63539) |
Antibody SKU: | PACO63539 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human V-type proton ATPase subunit D protein (1-247AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: U87 whole cell lysate, U251 whole cell lysate, A549 whole cell lysate, MCF-7 whole cell lysate. All lanes: ATP6V1D antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 29 kDa. Observed band size: 29 kDa. |
Background: | Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acid, fying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. |
Synonyms: | V-type proton ATPase subunit D (V-ATPase subunit D) (V-ATPase 28 kDa accessory protein) (Vacuolar proton pump subunit D), ATP6V1D, ATP6M VATD |
UniProt Protein Function: | ATP6V1D: Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase D subunit family. |
UniProt Protein Details: | Protein type:EC 3.6.3.14; Hydrolase; Energy Metabolism - oxidative phosphorylation Chromosomal Location of Human Ortholog: 14q23-q24.2 Cellular Component: centrosome; membrane; lysosomal membrane; cytosol; cilium Molecular Function:protein binding; ATPase activity, coupled to transmembrane movement of substances Biological Process: interaction with host; proton transport; cellular iron ion homeostasis; insulin receptor signaling pathway; cilium biogenesis; transferrin transport; transmembrane transport |
NCBI Summary: | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y5K8 |
NCBI GenInfo Identifier: | 10720351 |
NCBI Gene ID: | 51382 |
NCBI Accession: | Q9Y5K8.1 |
UniProt Secondary Accession: | Q9Y5K8,Q9Y688, B2RE33, |
UniProt Related Accession: | Q9Y5K8 |
Molecular Weight: | 247 |
NCBI Full Name: | V-type proton ATPase subunit D |
NCBI Synonym Full Names: | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
NCBI Official Symbol: | ATP6V1D |
NCBI Official Synonym Symbols: | VATD; VMA8; ATP6M |
NCBI Protein Information: | V-type proton ATPase subunit D; V-ATPase D subunit; V-ATPase subunit D; vacuolar H-ATPase subunit D; vacuolar proton pump D subunit; vacuolar proton pump subunit D; vacuolar ATP synthase subunit D; vacuolar proton-ATPase subunit D; V-ATPase 28 kDa accesso |
UniProt Protein Name: | V-type proton ATPase subunit D |
UniProt Synonym Protein Names: | V-ATPase 28 kDa accessory protein; Vacuolar proton pump subunit D |
UniProt Gene Name: | ATP6V1D |
UniProt Entry Name: | VATD_HUMAN |