ASB2 Antibody (PACO15827)
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주문- SKU:
- PACO15827
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ASB2 Antibody (PACO15827) |
Antibody SKU: | PACO15827 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human ASB2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15827(ASB2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid, induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Synonyms: | ankyrin repeat and SOCS box containing 2 |
UniProt Protein Function: | ASB2: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 14q31-q32 Molecular Function:protein binding Biological Process: positive regulation of defense response to virus by host; signal transduction |
NCBI Summary: | This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
UniProt Code: | Q96Q27 |
NCBI GenInfo Identifier: | 20531999 |
NCBI Gene ID: | 51676 |
NCBI Accession: | Q96Q27.1 |
UniProt Secondary Accession: | Q96Q27,Q9NSU5, Q9Y567, B2RDP9, B4E166, |
UniProt Related Accession: | Q96Q27 |
Molecular Weight: | 70,212 Da |
NCBI Full Name: | Ankyrin repeat and SOCS box protein 2 |
NCBI Synonym Full Names: | ankyrin repeat and SOCS box containing 2 |
NCBI Official Symbol: | ASB2 |
NCBI Official Synonym Symbols: | ASB-2 |
NCBI Protein Information: | ankyrin repeat and SOCS box protein 2 |
UniProt Protein Name: | Ankyrin repeat and SOCS box protein 2 |
Protein Family: | Anthranilate synthase |
UniProt Gene Name: | ASB2 |
UniProt Entry Name: | ASB2_HUMAN |
Antibodies |
Anti-ASB2 Antibody (CAB17923) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |