ARL4A Antibody (PACO15524)
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주문- SKU:
- PACO15524
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ARL4A Antibody (PACO15524) |
Antibody SKU: | PACO15524 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human ARL4A |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO15524(ARL4A Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal liver tissue, Primary antibody: PACO15524(ARL4A Antibody) at dilution 1/533, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15524(ARL4A Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene |
Synonyms: | ADP-ribosylation factor-like 4A |
UniProt Protein Function: | ARL4A: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. Belongs to the small GTPase superfamily. Arf family. |
UniProt Protein Details: | Protein type:Nucleolus; G protein, monomeric; G protein, monomeric, ARF Chromosomal Location of Human Ortholog: 7p21.3 Cellular Component: cytoplasm; plasma membrane; nucleolus; nucleus Molecular Function:protein binding; GTP binding Biological Process: small GTPase mediated signal transduction; brown fat cell differentiation |
NCBI Summary: | ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P40617 |
NCBI GenInfo Identifier: | 81295813 |
NCBI Gene ID: | 10124 |
NCBI Accession: | NP_001032241 |
UniProt Secondary Accession: | P40617,P80418, Q49AF5, A4D119, |
UniProt Related Accession: | P40617 |
Molecular Weight: | 22,615 Da |
NCBI Full Name: | ADP-ribosylation factor-like protein 4A |
NCBI Synonym Full Names: | ADP-ribosylation factor-like 4A |
NCBI Official Symbol: | ARL4A |
NCBI Official Synonym Symbols: | ARL4 |
NCBI Protein Information: | ADP-ribosylation factor-like protein 4A |
UniProt Protein Name: | ADP-ribosylation factor-like protein 4A |
UniProt Gene Name: | ARL4A |
UniProt Entry Name: | ARL4A_HUMAN |