ARHGEF5 Antibody (PACO15512)
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주문- SKU:
- PACO15512
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ARHGEF5 Antibody (PACO15512) |
Antibody SKU: | PACO15512 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human ARHGEF5 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15512(ARHGEF5 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15512(ARHGEF5 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. |
Synonyms: | Rho guanine nucleotide exchange factor (GEF) 5 |
UniProt Protein Function: | ARHGEF5: 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis; Oncoprotein Chromosomal Location of Human Ortholog: 7q35 Cellular Component: cytoplasm; nucleoplasm; nucleus; plasma membrane Molecular Function:GTP binding; guanyl-nucleotide exchange factor activity; protein binding Biological Process: positive regulation of JNK activity; positive regulation of stress fiber formation; positive regulation of transcription factor activity; regulation of actin cytoskeleton organization and biogenesis; regulation of cytoskeleton organization and biogenesis; regulation of GTPase activity |
NCBI Summary: | Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q12774 |
NCBI GenInfo Identifier: | 290457679 |
NCBI Gene ID: | 7984 |
NCBI Accession: | Q12774.3 |
UniProt Secondary Accession: | Q12774,Q6ZML7, A6NNJ2, |
UniProt Related Accession: | Q12774 |
Molecular Weight: | 60,056 Da |
NCBI Full Name: | Rho guanine nucleotide exchange factor 5 |
NCBI Synonym Full Names: | Rho guanine nucleotide exchange factor 5 |
NCBI Official Symbol: | ARHGEF5 |
NCBI Official Synonym Symbols: | P60; TIM; GEF5; TIM1 |
NCBI Protein Information: | rho guanine nucleotide exchange factor 5 |
UniProt Protein Name: | Rho guanine nucleotide exchange factor 5 |
UniProt Synonym Protein Names: | Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; Transforming immortalized mammary oncogene; p60 TIM |
Protein Family: | Rho guanine nucleotide exchange factor |
UniProt Gene Name: | ARHGEF5 |
UniProt Entry Name: | ARHG5_HUMAN |
Antibodies |
Anti-ARHGEF5 Antibody (CAB4196) |
Anti-ARHGEF5 Antibody (CAB17014) |
ARHGEF5 Antibody (PACO05379) |
ARHGEF5 Antibody (PACO07834) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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