ARFGAP3 Antibody (PACO43937)
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주문- SKU:
- PACO43937
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IP
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ARFGAP3 Antibody (PACO43937) |
Antibody SKU: | PACO43937 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IP |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human ADP-ribosylation factor GTPase-activating protein 3 protein (217-516AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: ARFGAP3 antibody at 4µg/ml. Lane 1: HepG2 whole cell lysate. Lane 2: Jurkat whole cell lysate. Lane 3: A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 57, 52 kDa. Observed band size: 57 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human liver cancer using PACO43937 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human breast cancer using PACO43937 at dilution of 1:100. |
Background: | GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. |
Synonyms: | ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3), ARFGAP3, ARFGAP1 |
UniProt Protein Function: | GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. |
NCBI Summary: | The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008] |
UniProt Code: | Q9NP61 |
NCBI GenInfo Identifier: | 21263420 |
NCBI Gene ID: | 26286 |
NCBI Accession: | Q9NP61.1 |
UniProt Secondary Accession: | Q9NP61,Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4 E9PB03, |
UniProt Related Accession: | Q9NP61 |
Molecular Weight: | 51,990 Da |
NCBI Full Name: | ADP-ribosylation factor GTPase-activating protein 3 |
NCBI Synonym Full Names: | ADP ribosylation factor GTPase activating protein 3 |
NCBI Official Symbol: | ARFGAP3 |
NCBI Official Synonym Symbols: | ARFGAP1 |
NCBI Protein Information: | ADP-ribosylation factor GTPase-activating protein 3 |
UniProt Protein Name: | ADP-ribosylation factor GTPase-activating protein 3 |
Protein Family: | ADP-ribosylation factor GTPase-activating protein |
UniProt Gene Name: | ARFGAP3 |
UniProt Entry Name: | ARFG3_HUMAN |