APBA1 Antibody (PACO19114)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO19114
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | APBA1 Antibody (PACO19114) |
Antibody SKU: | PACO19114 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human APBA1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 8%SDS-PAGE, Lysate: 50 μg, Lane 1-2: Human fetal brain tissue, mouse brain tissue, Primary antibody: PACO19114(APBA1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. |
Background: | The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A β peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. |
Synonyms: | amyloid β (A4) precursor protein-binding, family A, member 1 |
UniProt Protein Function: | Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. |
NCBI Summary: | The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q02410 |
NCBI GenInfo Identifier: | 22035548 |
NCBI Gene ID: | 320 |
NCBI Accession: | NP_001154.2 |
UniProt Secondary Accession: | Q02410,O14914, O60570, Q5VYR8, |
UniProt Related Accession: | Q02410 |
Molecular Weight: | 91,594 Da |
NCBI Full Name: | amyloid-beta A4 protein-binding family A member 1 |
NCBI Synonym Full Names: | amyloid beta precursor protein binding family A member 1 |
NCBI Official Symbol: | APBA1 |
NCBI Official Synonym Symbols: | X11; X11A; LIN10; MINT1; D9S411E; X11ALPHA |
NCBI Protein Information: | amyloid-beta A4 precursor protein-binding family A member 1 |
UniProt Protein Name: | Amyloid-beta A4 precursor protein-binding family A member 1 |
UniProt Synonym Protein Names: | Adapter protein X11alpha; Neuron-specific X11 protein; Neuronal Munc18-1-interacting protein 1; Mint-1 |
Protein Family: | Amyloid beta A4 precursor protein-binding family |
UniProt Gene Name: | APBA1 |
Antibodies |
Anti-APBA1 Antibody (CAB18582) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |