Anti-VSIG1 Antibody (CAB13875)
- SKU:
- CAB13875
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-VSIG1 Antibody |
| Antibody SKU: | CAB13875 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human VSIG1 (NP_872413.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BxP-C3, SGC-7901, OVCAR3, Mouse testis, Mouse stomach, Mouse pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human VSIG1 (NP_872413.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ASRE QLSI QWSF FHKK EMEP ISIY FSQG GQAV AIGQ FKDR ITGS NDPG NASI TISH MQPA DSGI YICD VNNP PDFL GQNQ GILN VSVL VKPS KPLC SVQG RPET GHTI SLSC LSAL GTPS PVYY WHKL EGRD IVPV KENF NPTT GILV IGNL TNFE QGYY QCTA INRL GNSS CEID LTSS H |
| Gene ID: | 340547 |
| Uniprot: | Q86XK7 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 41kDa/45kDa |
| Observed MW: | 65kDa |
| Synonyms: | VSIG1, 1700062D20Rik, GPA34, dJ889N15.1 |
| Background: | This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | VSIG1: 2 isoforms of the human protein are produced by alternative splicing |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: Xq22.3 |
| NCBI Summary: | This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] |
| UniProt Code: | Q86XK7 |
| NCBI GenInfo Identifier: | 74759503 |
| NCBI Gene ID: | 340547 |
| NCBI Accession: | Q86XK7.1 |
| UniProt Secondary Accession: | Q86XK7,Q6MZS4, C9J4P2, |
| UniProt Related Accession: | Q86XK7 |
| Molecular Weight: | 45,807 Da |
| NCBI Full Name: | V-set and immunoglobulin domain-containing protein 1 |
| NCBI Synonym Full Names: | V-set and immunoglobulin domain containing 1 |
| NCBI Official Symbol: | VSIG1 |
| NCBI Official Synonym Symbols: | GPA34; dJ889N15.1; 1700062D20Rik |
| NCBI Protein Information: | V-set and immunoglobulin domain-containing protein 1 |
| UniProt Protein Name: | V-set and immunoglobulin domain-containing protein 1 |
| UniProt Synonym Protein Names: | Cell surface A33 antigen; Glycoprotein A34 |
| Protein Family: | V-set and immunoglobulin domain-containing protein |
| UniProt Gene Name: | VSIG1 |
| UniProt Entry Name: | VSIG1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using VSIG1 antibody (CAB13875) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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