Anti-UAP1 Antibody (RACO0536)
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주문- SKU:
- RACO0536
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- WB
- Application:
- ELISA
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Product Name: | UAP1 Antibody |
Product SKU: | RACO0536 |
Size: | 50ul |
Host Species: | Homo sapiens (Human) |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:5000 |
Species Reactivity: | Human |
Immunogen: | A synthesized peptide derived from human UAP1 |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | Affinity-chromatography |
Clonality: | Monoclonal |
Isotype: | Rabbit IgG |
Conjugate: | Non-conjugated |
Background: | Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P. |
Synonyms: | UDP-N-acetylhexosamine pyrophosphorylase (Antigen X) (AGX) (Sperm-associated antigen 2) [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83) (AGX-1), UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (AGX-2)], UAP1, SPAG2 |
Western Blot. Positive WB detected in K562 whole cell lysate All lanes UAP1 antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1:50000 dilution. Predicted band size: 59, 58, 59 kDa. Observed band size: 59 kDa. |
UniProt Protein Function: | UAP1: Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P. Belongs to the UDPGP type 1 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transferase; EC 2.7.7.23; EC 2.7.7.83; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 1q23.3 Cellular Component: nucleoplasm; cytoplasm; plasma membrane; cytosol Molecular Function:UDP-N-acetylglucosamine diphosphorylase activity; carbohydrate binding Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; UDP-N-acetylglucosamine biosynthetic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification |
UniProt Code: | Q16222 |
NCBI GenInfo Identifier: | 68846235 |
NCBI Gene ID: | 6675 |
NCBI Accession: | Q16222.3 |
UniProt Secondary Accession: | Q16222,Q91YN5, |
UniProt Related Accession: | Q16222 |
Molecular Weight: | |
NCBI Full Name: | UDP-N-acetylhexosamine pyrophosphorylase |
NCBI Synonym Full Names: | UDP-N-acetylglucosamine pyrophosphorylase 1 |
NCBI Official Symbol: | UAP1Â Â |
NCBI Official Synonym Symbols: | AGX; AGX1; AGX2; SPAG2Â Â |
NCBI Protein Information: | UDP-N-acetylhexosamine pyrophosphorylase |
UniProt Protein Name: | UDP-N-acetylhexosamine pyrophosphorylase |
UniProt Synonym Protein Names: | Antigen X; AGX; Sperm-associated antigen 2Including the following 2 domains:UDP-N-acetylgalactosamine pyrophosphorylase (EC:2.7.7.83)Alternative name(s):AGX-1 |
Protein Family: | UDP-N-acetylhexosamine pyrophosphorylase |
UniProt Gene Name: | UAP1Â Â |
UniProt Entry Name: | UAP1_HUMAN |