Anti-TRIM33 Antibody (MACO0369)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- MACO0369
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Dog
- Reactivity:
- Pig
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Application:
- ELISA
- Application:
- WB
- Application:
- ICC
- Antibody type:
- Monoclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Product Name: | Anti-TRIM33 Antibody |
Product Sku: | MACO0369 |
Size: | 100ul |
Host Species: | Mouse |
Tested Applications: | ELISA, WB, ICC |
Recommended Dilutions: | WB:1:500-1:5000, ICC:1:50-1:200 |
Species Reactivity: | Human, Dog, Pig, Mouse, Rat |
Immunogen: | Recombinant fragment, corresponding to amino acids 712aa-853aa of human TRIM33 (C-terminus). |
Form: | Liquid |
Storage Buffer: | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol |
Purification Method: | Antigen Affinity Purified |
Clonality: | Monoclonal |
Isotype: | IgG2a |
Conjugate: | Non-conjugated |
Background: | |
Synonyms: | E3 ubiquitin-protein ligase TRIM33 TIF1-gamma protein Rfg7 ectodermin homolog RET-fused gene 7 protein tripartite motif-containing 33 transcriptional intermediary factor 1 gamma |
UniProt Protein Function: | TIF1G: an atypical protein kinase that functions as a transcriptional repressor. Translocation with RET generates the TRIM33/RET (PTC7) oncogene. The protein is a member of the tripartite motif family. This motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Two splice variant isoforms have been described. |
UniProt Protein Details: | Protein type:Kinase, protein; Ubiquitin ligase; Ligase; EC 6.3.2.19; Ubiquitin conjugating system; Transcription, coactivator/corepressor; EC 6.3.2.-; Protein kinase, atypical; ATYPICAL group; TIF1 family Chromosomal Location of Human Ortholog: 1p13.1 Cellular Component: intracellular membrane-bound organelle; nucleoplasm; nucleus Molecular Function:protein binding; ubiquitin-protein ligase activity Biological Process: negative regulation of BMP signaling pathway; negative regulation of transcription from RNA polymerase II promoter; protein ubiquitination; regulation of transforming growth factor beta receptor signaling pathway Disease: Thyroid Carcinoma, Papillary |
NCBI Summary: | The protein encoded by this gene is thought to be a transcriptional corepressor. However, molecules that interact with this protein have not yet been identified. The protein is a member of the tripartite motif family. This motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Three alternatively spliced transcript variants for this gene have been described, however, the full-length nature of one variant has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UPN9 |
NCBI GenInfo Identifier: | 313104270 |
NCBI Gene ID: | 51592 |
NCBI Accession: | Q9UPN9.3 |
UniProt Secondary Accession: | Q9UPN9,O95855, Q5TG72, Q5TG73, Q5TG74, Q9C017, Q9UJ79 |
UniProt Related Accession: | Q9UPN9 |
Molecular Weight: | 120,541 Da |
NCBI Full Name: | E3 ubiquitin-protein ligase TRIM33 |
NCBI Synonym Full Names: | tripartite motif containing 33 |
NCBI Official Symbol: | TRIM33 |
NCBI Official Synonym Symbols: | ECTO; PTC7; RFG7; TF1G; TIF1G; TIFGAMMA; TIF1GAMMA |
NCBI Protein Information: | E3 ubiquitin-protein ligase TRIM33 |
UniProt Protein Name: | E3 ubiquitin-protein ligase TRIM33 |
UniProt Synonym Protein Names: | Ectodermin homolog; RET-fused gene 7 protein; Protein Rfg7; Transcription intermediary factor 1-gamma; TIF1-gamma; Tripartite motif-containing protein 33 |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | TRIM33 |
UniProt Entry Name: | TRI33_HUMAN |