Anti-TRIB1 Antibody (CAB10134)
- SKU:
- CAB10134
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-TRIB1 Antibody |
| Antibody SKU: | CAB10134 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 203-372 of human TRIB1 (NP_079471.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:4000 |
| Reactivity: | Human |
| Positive Samples: | U-87MG, BxPC-3, Raji |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 203-372 of human TRIB1 (NP_079471.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LGDL KLRK FVFS TEER TQLR LESL EDTH IMKG EDDA LSDK HGCP AYVS PEIL NTTG TYSG KAAD VWSL GVML YTLL VGRY PFHD SDPS ALFS KIRR GQFC IPEH ISPK ARCL IRSL LRRE PSER LTAP EILL HPWF ESVL EPGY IDSE IGTS DQIV PEYQ EDSD ISSF FC |
| Gene ID: | 10221 |
| Uniprot: | Q96RU8 |
| Cellular Location: | |
| Calculated MW: | 23kDa/41kDa |
| Observed MW: | 38kDa |
| Synonyms: | TRIB1, C8FW, GIG-2, GIG2, SKIP1, TRB-1, TRB1 |
| Background: |
| UniProt Protein Function: | TRB1: Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily. |
| UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, CAMK; CAMK group; Trbl family Chromosomal Location of Human Ortholog: 8q24.13 Cellular Component: cytoplasm; nucleus Molecular Function:ATP binding; mitogen-activated protein kinase kinase binding; protein binding; protein kinase activity; protein kinase inhibitor activity; transcription factor binding; ubiquitin protein ligase binding; ubiquitin-protein ligase regulator activity Biological Process: JNK cascade; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of protein kinase activity; negative regulation of smooth muscle cell migration; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein amino acid phosphorylation; regulation of MAP kinase activity; response to lipopolysaccharide |
| UniProt Code: | Q96RU8 |
| NCBI GenInfo Identifier: | 83305929 |
| NCBI Gene ID: | 10221 |
| NCBI Accession: | Q96RU8.2 |
| UniProt Secondary Accession: | Q96RU8,O15180, Q9H2Y8, B4DMM6, C5HU08, |
| UniProt Related Accession: | Q96RU8 |
| Molecular Weight: | 23,473 Da |
| NCBI Full Name: | Tribbles homolog 1 |
| NCBI Synonym Full Names: | tribbles pseudokinase 1 |
| NCBI Official Symbol: | TRIB1 |
| NCBI Official Synonym Symbols: | C8FW; GIG2; TRB1; GIG-2; SKIP1; TRB-1 |
| NCBI Protein Information: | tribbles homolog 1 |
| UniProt Protein Name: | Tribbles homolog 1 |
| UniProt Synonym Protein Names: | G-protein-coupled receptor-induced gene 2 protein; GIG-2; SKIP1 |
| UniProt Gene Name: | TRIB1 |
| UniProt Entry Name: | TRIB1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TRIB1 antibody (CAB10134) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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