Anti-TIMM44 Antibody (CAB17446)
- SKU:
- CAB17446
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-TIMM44 Antibody |
| Antibody SKU: | CAB17446 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 153-452 of human TIMM44 (NP_006342.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, K562, mouse liver, rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 153-452 of human TIMM44 (NP_006342.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AKTA KQSA ESVS KGGE KLGR TAAF RALS QGVE SVKK EIDD SVLG QTGP YRRP QRLR KRTE FAGD KFKE EKVF EPNE EALG VVLH KDSK WYQQ WKDF KENN VVFN RFFE MKMK YDES DNAF IRAS RALT DKVT DLLG GLFS KTEM SEVL TEIL RVDP AFDK DRFL KQCE NDII PNVL EAMI SGEL DILK DWCY EATY SQLA HPIQ QAKA LGLQ FHSR ILDI DNVD LAMG KMME QGPV LIIT FQAQ LVMV VRNP KGEV VEGD PDKV LRML YVWA LCRD QDEL NPYA AWRL LDIS ASST EQIL |
| Gene ID: | 10469 |
| Uniprot: | O43615 |
| Cellular Location: | |
| Calculated MW: | 51kDa |
| Observed MW: | 51kDa |
| Synonyms: | TIM44, TIMM44 |
| Background: | This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma. |
| UniProt Code: | O43615 |
| NCBI GenInfo Identifier: | 33636719 |
| NCBI Gene ID: | 10469 |
| NCBI Accession: | NP_006342.2 |
| UniProt Secondary Accession: | O43615,O35857, O35094, |
| UniProt Related Accession: | O43615 |
| Molecular Weight: | 51,356 Da |
| NCBI Full Name: | mitochondrial import inner membrane translocase subunit TIM44 |
| NCBI Synonym Full Names: | translocase of inner mitochondrial membrane 44 homolog (yeast) |
| NCBI Official Symbol: | TIMM44 |
| NCBI Official Synonym Symbols: | TIM44 |
| NCBI Protein Information: | mitochondrial import inner membrane translocase subunit TIM44; mitochondrial inner membrane translocase |
| UniProt Protein Name: | Mitochondrial import inner membrane translocase subunit TIM44 |
| UniProt Gene Name: | TIMM44 |
| UniProt Entry Name: | TIM44_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TIMM44 antibody (CAB17446) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
 | Immunofluorescence analysis of L929 cells using TIMM44 antibody (CAB17446) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of U-2 OS cells using TIMM44 antibody (CAB17446) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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