Anti-TIMM23 Antibody (CAB8688)
- SKU:
- CAB8688
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-TIMM23 Antibody |
| Antibody SKU: | CAB8688 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human TIMM23 (NP_006318.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SH-SY5Y, SW620, HepG2, MCF7, Mouse heart, Rat brain, Rat heart, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human TIMM23 (NP_006318.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEGG GGSG NKTT GGLA GFFG AGGA GYSH ADLA GVPL TGMN PLSP YLNV DPRY LVQD TDEF ILPT GANK TRGR FELA FFTI GGCC MTGA AFGA MNGL RLGL KETQ NMAW SKPR NVQI LNMV TRQG ALWA NTLG SLAL LYSA FGVI IEKT RGAE DDLN TVAA GTMT GMLY KCTG GLRG IARG GLTG LTLT SLYA LYNN WEHM KGSL LQQS L |
| Gene ID: | 100287932 |
| Uniprot: | O14925 |
| Cellular Location: | Mitochondrion inner membrane, Multi-pass membrane protein |
| Calculated MW: | 21kDa |
| Observed MW: | 21kDa |
| Synonyms: | TIMM23, TIM23 |
| Background: | The protein encoded by this gene is part of a complex located in the inner mitochondrial membrane that mediates the transport of transit peptide-containing proteins across the membrane. Multiple transcript variants, one protein-coding and others not protein-coding, have been found for this gene. |
| UniProt Protein Function: | TIMM23: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Belongs to the Tim17/Tim22/Tim23 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Mitochondrial Chromosomal Location of Human Ortholog: 10q11.23 Cellular Component: integral to mitochondrial inner membrane; mitochondrial inner membrane; mitochondrial inner membrane presequence translocase complex; mitochondrial intermembrane space; mitochondrion Molecular Function:protein binding; protein channel activity Biological Process: protein import into mitochondrial matrix; protein targeting to mitochondrion |
| NCBI Summary: | The protein encoded by this gene is part of a complex located in the inner mitochondrial membrane that mediates the transport of transit peptide-containing proteins across the membrane. Multiple transcript variants, one protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jul 2012] |
| UniProt Code: | O14925 |
| NCBI GenInfo Identifier: | 18201964 |
| NCBI Gene ID: | 100287932 |
| NCBI Accession: | O14925.1 |
| UniProt Secondary Accession: | O14925,Q53FF8, Q5T1E6, Q6P5S5, |
| UniProt Related Accession: | O14925 |
| Molecular Weight: | 21,943 Da |
| NCBI Full Name: | Mitochondrial import inner membrane translocase subunit Tim23 |
| NCBI Synonym Full Names: | translocase of inner mitochondrial membrane 23 |
| NCBI Official Symbol: | TIMM23 |
| NCBI Official Synonym Symbols: | TIM23 |
| NCBI Protein Information: | mitochondrial import inner membrane translocase subunit Tim23 |
| UniProt Protein Name: | Mitochondrial import inner membrane translocase subunit Tim23 |
| Protein Family: | Mitochondrial import inner membrane translocase |
| UniProt Gene Name: | TIMM23 |
| UniProt Entry Name: | TIM23_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TIMM23 antibody (CAB8688) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
 | Western blot analysis of extracts of Mouse heart, using TIMM23 antibody (CAB8688) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
 | Western blot analysis of extracts of various cell lines, using TIMM23 antibody (CAB8688) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
