Anti-SSC4D Antibody (CAB15957)
- SKU:
- CAB15957
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-SSC4D Antibody |
| Antibody SKU: | CAB15957 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 446-575 of human SSC4D (NP_542782.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, HepG2, Mouse liver, Mouse brain, Rat liver, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 446-575 of human SSC4D (NP_542782.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PEEL GLQV QQDG SETT RVPT PRPR DGHL RLVN GAHR CEGR VELY LGQR WGTV CDDA WDLR AAGV LCRQ LGCG QALA APGE AHFG PGRG PILL DNVK CRGE ESAL LLCS HIRW DAHN CDHS EDAS VLCQ PS |
| Gene ID: | 136853 |
| Uniprot: | Q8WTU2 |
| Cellular Location: | Secreted |
| Calculated MW: | 29kDa/60kDa |
| Observed MW: | 61kDa |
| Synonyms: | SSC4D, S4D-SRCRB, SRCRB-S4D, SRCRB4D |
| Background: | The scavenger receptor cysteine-rich (SRCR) superfamily is an ancient and highly conserved group of cell surface and/or secreted proteins, some of which are involved in the development of the immune system and the regulation of both innate and adaptive immune responses. Group B SRCR domains usually contain 8 regularly spaced cysteines that give rise to a well-defined intradomain disulfide-bond pattern. |
| UniProt Protein Function: | SRCRB4D: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 7q11.23 |
| NCBI Summary: | The scavenger receptor cysteine-rich (SRCR) superfamily is an ancient and highly conserved group of cell surface and/or secreted proteins, some of which are involved in the development of the immune system and the regulation of both innate and adaptive immune responses. Group B SRCR domains usually contain 8 regularly spaced cysteines that give rise to a well-defined intradomain disulfide-bond pattern.[supplied by OMIM, Apr 2004] |
| UniProt Code: | Q8WTU2 |
| NCBI GenInfo Identifier: | 74751496 |
| NCBI Gene ID: | 136853 |
| NCBI Accession: | Q8WTU2.1 |
| UniProt Secondary Accession: | Q8WTU2,Q2HIZ5, Q6ZMG3, Q96BF5, |
| UniProt Related Accession: | Q8WTU2 |
| Molecular Weight: | 29,264 Da |
| NCBI Full Name: | Scavenger receptor cysteine-rich domain-containing group B protein |
| NCBI Synonym Full Names: | scavenger receptor cysteine rich family member with 4 domains |
| NCBI Official Symbol: | SSC4D |
| NCBI Official Synonym Symbols: | SRCRB4D; S4D-SRCRB; SRCRB-S4D |
| NCBI Protein Information: | scavenger receptor cysteine-rich domain-containing group B protein |
| UniProt Protein Name: | Scavenger receptor cysteine-rich domain-containing group B protein |
| UniProt Synonym Protein Names: | Four scavenger receptor cysteine-rich domains-containing protein |
| UniProt Gene Name: | SSC4D |
| UniProt Entry Name: | SRB4D_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SSC4D antibody (CAB15957) at 1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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