Anti-SGCZ Antibody (CAB15958)
- SKU:
- CAB15958
- Product type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-SGCZ Antibody |
| Antibody SKU: | CAB15958 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 83-312 of human SGCZ (NP_631906.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse heart, Rat heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 83-312 of human SGCZ (NP_631906.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NLRV TKKG IRLE GISE FLLP LYVK EIHS RKDS PLVL QSDR NVTV NARN HMGQ LTGQ LTIG ADAV EAQC KRFE VRAS EDGR VLFS ADED EITI GAEK LKVT GTEG AVFG HSVE TPHI RAEP SQDL RLES PTRS LIME APRG VQVS AAAG DFKA TCRK ELHL QSTE GEIF LNAE TIKL GNLP TGSF SSSS PSSS SSRQ TVYE LCVC PNGK LYLS PAGV GSTC QSSS NICL WS |
| Gene ID: | 137868 |
| Uniprot: | Q96LD1 |
| Cellular Location: | Cell membrane, Cytoplasm, Single-pass type II membrane protein, cytoskeleton, sarcolemma |
| Calculated MW: | 32kDa/34kDa |
| Observed MW: | 38kDa |
| Synonyms: | SGCZ, ZSG1 |
| Background: | The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix. |
| NCBI Summary: | The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96LD1 |
| NCBI GenInfo Identifier: | 115528889 |
| NCBI Gene ID: | 137868 |
| NCBI Accession: | AAI25038.1 |
| UniProt Related Accession: | Q96LD1 |
| Molecular Weight: | 32kDa; 34kDa |
| NCBI Full Name: | SGCZ protein |
| NCBI Synonym Full Names: | sarcoglycan zeta |
| NCBI Official Symbol: | SGCZ |
| NCBI Official Synonym Symbols: | ZSG1 |
| NCBI Protein Information: | zeta-sarcoglycan |
| UniProt Protein Name: | Zeta-sarcoglycan |
| UniProt Synonym Protein Names: | ZSG1 |
| Protein Family: | Zeta-sarcoglycan |
| UniProt Gene Name: | SGCZ |
| UniProt Entry Name: | SGCZ_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SGCZ antibody (CAB15958) at 1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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