Anti-RAB27B Antibody (CAB10389)
- SKU:
- CAB10389
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-RAB27B Antibody |
| Antibody SKU: | CAB10389 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human RAB27B (NP_004154.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, A375, Mouse lung, Mouse brain, Rat brain, Rat spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human RAB27B (NP_004154.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MTDG DYDY LIKL LALG DSGV GKTT FLYR YTDN KFNP KFIT TVGI DFRE KRVV YNAQ GPNG SSGK AFKV HLQL WDTA GQER FRSL TTAF FRDA MGFL LMFD LTSQ QSFL NVRN WMSQ LQAN AYCE NPDI VLIG NKAD LPDQ REVN ERQA RELA DKYG IPYF ETSA ATGQ NVEK AVET LLDL IMKR MEQC VEKT QIPD TVNG GNSG NLDG EKPP EKKC IC |
| Gene ID: | 5874 |
| Uniprot: | O00194 |
| Cellular Location: | Lipid-anchor, Membrane |
| Calculated MW: | 24kDa |
| Observed MW: | 25kDa |
| Synonyms: | RAB27B, C25KG |
| Background: |
| UniProt Protein Function: | RAB27B: May be involved in targeting uroplakins to urothelial apical membranes. Belongs to the small GTPase superfamily. Rab family. |
| UniProt Protein Details: | Protein type:G protein, monomeric, Rab; G protein, monomeric Chromosomal Location of Human Ortholog: 18q21.2 Cellular Component: Golgi stack; melanosome; secretory granule; trans-Golgi network transport vesicle Molecular Function:GDP binding; GTP binding; GTPase activity; myosin V binding; protein binding; protein domain specific binding Biological Process: melanosome transport; positive regulation of exocytosis |
| NCBI Summary: | Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking (Chen et al., 1997 [PubMed 9066979]).[supplied by OMIM, Nov 2010] |
| UniProt Code: | O00194 |
| NCBI GenInfo Identifier: | 14917027 |
| NCBI Gene ID: | 5874 |
| NCBI Accession: | O00194.4 |
| UniProt Secondary Accession: | O00194,Q9BZB6, B2RAB0, |
| UniProt Related Accession: | O00194 |
| Molecular Weight: | 24,608 Da |
| NCBI Full Name: | Ras-related protein Rab-27B |
| NCBI Synonym Full Names: | RAB27B, member RAS oncogene family |
| NCBI Official Symbol: | RAB27B |
| NCBI Official Synonym Symbols: | C25KG |
| NCBI Protein Information: | ras-related protein Rab-27B |
| UniProt Protein Name: | Ras-related protein Rab-27B |
| UniProt Synonym Protein Names: | C25KG |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB27B |
| UniProt Entry Name: | RB27B_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RAB27B antibody (CAB10389) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
Related Products
