Anti-PRDX6 항체 (CAB2031)

Antibody Name:	Anti-PRDX6 Antibody
Antibody SKU:	CAB2031
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC IF
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human PRDX6 (NP_004896.1).

Application:	WB IHC IF
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:	Human, Mouse
Positive Samples:	HeLa, PC-3, K-562, BT-474, Mouse liver, Mouse heart

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human PRDX6 (NP_004896.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MPGG LLLG DVAP NFEA NTTV GRIR FHDF LGDS WGIL FSHP RDFT PVCT TELG RAAK LAPE FAKR NVKL IALS IDSV EDHL AWSK DINA YNCE EPTE KLPF PIID DRNR ELAI LLGM LDPA EKDE KGMP VTAR VVFV FGPD KKLK LSIL YPAT TGRN FDEI LRVV ISLQ LTAE KRVA TPVD WKDG DSVM VLPT IPEE EAKK LFPK GVFT KELP SGKK YLRY TPQP
Gene ID:	9588
Uniprot:	P30041
Cellular Location:	Cytoplasm, Cytoplasmic vesicle, Lysosome
Calculated MW:	25kDa
Observed MW:	27kDa

Synonyms:

PRDX6, 1-Cys, AOP2, HEL-S-128m, NSGPx, PRX, aiPLA2, p29

Background:

The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

UniProt Protein Function:	PRDX6: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Belongs to the AhpC/TSA family. Rehydrin subfamily.
UniProt Protein Details:	Protein type:Amino Acid Metabolism - phenylalanine; Oxidoreductase; Energy Metabolism - methane; EC 1.11.1.9; EC 1.11.1.15; Phospholipase Chromosomal Location of Human Ortholog: 1q25.1 Cellular Component: extracellular space; membrane; lysosome; cytoplasmic membrane-bound vesicle; cytoplasm; cytosol Molecular Function:antioxidant activity; phospholipase A2 activity; protein binding; peroxiredoxin activity; glutathione peroxidase activity Biological Process: response to reactive oxygen species; phospholipid catabolic process; hydrogen peroxide catabolic process; response to oxidative stress
NCBI Summary:	The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]
UniProt Code:	P30041
NCBI GenInfo Identifier:	1718024
NCBI Gene ID:	9588
NCBI Accession:	P30041.3
UniProt Secondary Accession:	P30041,P32077, Q5TAH4, Q5ZEZ8, A8JZY7,
UniProt Related Accession:	P30041
Molecular Weight:	Observed: 27kDaCalculated: 25kDa
NCBI Full Name:	Peroxiredoxin-6
NCBI Synonym Full Names:	peroxiredoxin 6
NCBI Official Symbol:	PRDX6
NCBI Official Synonym Symbols:	PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m
NCBI Protein Information:	peroxiredoxin-6; 1-Cys PRX; 24 kDa protein; 1-Cys peroxiredoxin; antioxidant protein 2; liver 2D page spot 40; red blood cells page spot 12; non-selenium glutathione peroxidase; acidic calcium-independent phospholipase A2; epididymis secretory sperm binding protein Li 128m
UniProt Protein Name:	Peroxiredoxin-6
UniProt Synonym Protein Names:	1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2 (EC:3.1.1.-); aiPLA2; Antioxidant protein 2; Liver 2D page spot 40; Non-selenium glutathione peroxidase (EC:1.11.1.9); NSGPx; Red blood cells page spot 12
Protein Family:	Peroxiredoxin
UniProt Gene Name:	PRDX6
UniProt Entry Name:	PRDX6_HUMAN

	Western blot analysis of extracts of various cell lines, using PRDX6 antibody (CAB2031) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
	Immunofluorescence analysis of HeLa cells using PRDX6 antibody (CAB2031).

Antibodies	ELISA Kits
Anti-PRDX6 Antibody (CAB4286)	Human PRDX6 / Peroxiredoxin-6 ELISA Kit
PRDX6 Antibody (PACO11454)	Human Peroxiredoxin-6 (PRDX6) ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)