| UniProt Protein Function: | PIN4: Isoform 1 is involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to tightly bent AT-rich stretches of double-stranded DNA. Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily. 2 isoforms of the human protein are produced by alternative promoter. |
| UniProt Protein Details: | Protein type:Nucleolus; Isomerase; Mitochondrial; EC 5.2.1.8 Chromosomal Location of Human Ortholog: Xq13 Molecular Function:protein binding |
| NCBI Summary: | This gene encodes a member of the parvulin subfamily of the peptidyl-prolyl cis/trans isomerase protein family. The encoded protein catalyzes the isomerization of peptidylprolyl bonds, and may play a role in the cell cycle, chromatin remodeling, and/or ribosome biogenesis. The encoded protein may play an additional role in the mitochondria. [provided by RefSeq, Dec 2009] |
| UniProt Code: | Q9Y237 |
| NCBI GenInfo Identifier: | 20139299 |
| NCBI Gene ID: | 5303 |
| NCBI Accession: | Q9Y237.1 |
| UniProt Secondary Accession: | Q9Y237,Q0D2H3, Q3MHV0, Q52M21, Q5HYW6, Q6IRW4, A8E0G6 B3KXM0, F5H1P5, |
| UniProt Related Accession: | Q9Y237 |
| Molecular Weight: | 14,179 Da |
| NCBI Full Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 |
| NCBI Synonym Full Names: | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| NCBI Official Symbol: | PIN4 |
| NCBI Official Synonym Symbols: | EPVH; PAR14; PAR17 |
| NCBI Protein Information: | peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 |
| UniProt Protein Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 |
| UniProt Synonym Protein Names: | Parvulin-14; Par14; hPar14; Parvulin-17; Par17; hPar17; Peptidyl-prolyl cis-trans isomerase Pin4; PPIase Pin4; Peptidyl-prolyl cis/trans isomerase EPVH; hEPVH; Rotamase Pin4 |
| Protein Family: | Peptidyl-prolyl cis-trans isomerase |
| UniProt Gene Name: | PIN4 |
| UniProt Entry Name: | PIN4_HUMAN |
