Anti-PCDH8 Antibody (CAB14250)
- SKU:
- CAB14250
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-PCDH8 Antibody |
| Antibody SKU: | CAB14250 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 450-750 of human PCDH8 (NP_002581.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-251MG, SH-SY5Y, Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 450-750 of human PCDH8 (NP_002581.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VTAA SLDR ERIA EYNL TLVA EDRG APPL RTVR PYTV RVGD ENDN APLF TRPV YEVS VREN NPPG AYLA TVAA RDRD LGRN GQVT YRLL EAEV GRAG GAVS TYVS VDPA TGAI YALR SFDY ETLR QLDV RIQA SDGG SPQL SSSA LVQV RVLD QNDH APVL VHPA PANG SLEV AVPG RTAK DTVV ARVQ ARDA DEGA NGEL AFEL QQQE PREA FAIG RRTG EILL TGDL SQEP PGRV FRAL LVIS DGGR PPLT TTAT VSFV VTAG GGRG PAAP ASAG SPER SRPP GSRL GVSG SVLQ WDTP L |
| Gene ID: | 5100 |
| Uniprot: | O95206 |
| Cellular Location: | Cell junction, Cell membrane, Cell projection, Single-pass type I membrane protein, dendrite, postsynaptic cell membrane, presynaptic cell membrane, synapse |
| Calculated MW: | 103kDa/113kDa |
| Observed MW: | 113kDa |
| Synonyms: | PCDH8, ARCADLIN, PAPC |
| Background: | This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails. |
| UniProt Code: | O95206 |
| NCBI GenInfo Identifier: | 6631102 |
| NCBI Gene ID: | |
| NCBI Accession: | NP_002581 |
| Molecular Weight: | |
| NCBI Full Name: | protocadherin-8 isoform 1 |
| UniProt Protein Name: | Protocadherin-8 |
| UniProt Synonym Protein Names: | Arcadlin |
| Protein Family: | Protocadherin |
| UniProt Gene Name: | PCDH8 |
| UniProt Entry Name: | PCDH8_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PCDH8 antibody (CAB14250) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
Anti-SLC20A2 Antibody (CAB6739)
Anti-CHRDL1 Antibody (CAB15204)
