Anti-PACSIN2 Antibody (CAB7781)

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SKU:
CAB7781
Product type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Frequently bought together:

Description

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Antibody Name:Anti-PACSIN2 Antibody
Antibody SKU:CAB7781
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 240-410 of human PACSIN2 (NP_009160.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:BT-474, HepG2, Mouse lung, Mouse heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 240-410 of human PACSIN2 (NP_009160.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RLRF FREV LLEV QKHL DLSN VAGY KAIY HDLE QSIR AADA VEDL RWFR ANHG PGMA MNWP QFEE WSAD LNRT LSRR EKKK ATDG VTLT GINQ TGDQ SLPS KPSS TLNV PSNP AQSA QSQS SYNP FEDE DDTG STVS EKDD TKAK NVSS YEKT QSYP TDWS DDES NNPF SST
Gene ID:11252
Uniprot:Q9UNF0
Cellular Location:Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle membrane, Early endosome, Membrane, Peripheral membrane protein, Recycling endosome membrane, caveola, cytoskeleton, ruffle membrane
Calculated MW:51kDa/55kDa
Observed MW:56kDa
Synonyms:PACSIN2, SDPII
Background:This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:PACSIN2: May play a role in vesicle formation and transport. Belongs to the PACSIN family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 22q13.2-q13.33

Cellular Component: caveola; cytoplasm; extrinsic to membrane; focal adhesion; intracellular membrane-bound organelle; nucleoplasm; recycling endosome membrane

Molecular Function:identical protein binding; protein binding; transporter activity

Biological Process: cell projection morphogenesis; regulation of endocytosis

NCBI Summary:This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
UniProt Code:Q9UNF0
NCBI GenInfo Identifier:22256968
NCBI Gene ID:11252
NCBI Accession:Q9UNF0.2
UniProt Secondary Accession:Q9UNF0,O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2,
UniProt Related Accession:Q9UNF0
Molecular Weight:51,353 Da
NCBI Full Name:Protein kinase C and casein kinase substrate in neurons protein 2
NCBI Synonym Full Names:protein kinase C and casein kinase substrate in neurons 2
NCBI Official Symbol:PACSIN2  
NCBI Official Synonym Symbols:SDPII  
NCBI Protein Information:protein kinase C and casein kinase substrate in neurons protein 2
UniProt Protein Name:Protein kinase C and casein kinase substrate in neurons protein 2
UniProt Synonym Protein Names:Syndapin-2; Syndapin-II
Protein Family:Protein kinase C and casein kinase substrate in neurons protein
UniProt Gene Name:PACSIN2  
UniProt Entry Name:PACN2_HUMAN
Anti-PACSIN2 Antibody (CAB7781)Western blot analysis of extracts of various cell lines, using PACSIN2 antibody (CAB7781) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.

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