Anti-OLFM1 Antibody (CAB0261)
- SKU:
- CAB0261
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-OLFM1 Antibody |
| Antibody SKU: | CAB0261 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-220 of human OLFM1 (NP_055094.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse brain, MCF7, A-549, SW480 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-220 of human OLFM1 (NP_055094.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | IEVL DRRT QRDL QYVE KMEN QMKG LESK FKQV EESH KQHL ARQF KAIK AKMD ELRP LIPV LEEY KADA KLVL QFKE EVQN LTSV LNEL QEEI GAYD YDEL QSRV SNLE ERLR ACMQ KLAC GKLT GISD PVT |
| Gene ID: | 10439 |
| Uniprot: | Q99784 |
| Cellular Location: | Cell junction, Cell projection, Endoplasmic reticulum, Perikaryon, Secreted, axon, synapse |
| Calculated MW: | 15-17kDa/52-55kDa |
| Observed MW: | 72kDa |
| Synonyms: | OLFM1, AMY, NOE1, NOELIN1, OlfA, noelin |
| Background: | This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | OLFM1: Seems to play an important role in regulating the production of neural crest cells by the neural tube. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell development/differentiation; Cell adhesion Chromosomal Location of Human Ortholog: 9q34.3 Cellular Component: extracellular space; synapse; cell junction Molecular Function:protein binding; beta-amyloid binding Biological Process: nervous system development; protein oligomerization |
| NCBI Summary: | This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99784 |
| NCBI GenInfo Identifier: | 206729935 |
| NCBI Gene ID: | 10439 |
| NCBI Accession: | Q99784.4 |
| UniProt Secondary Accession: | Q99784,Q53XZ8, Q6IMJ4, Q6IMJ5, Q8N8R0, Q969S7, Q99452 |
| UniProt Related Accession: | Q99784 |
| Molecular Weight: | 485 |
| NCBI Full Name: | Noelin |
| NCBI Synonym Full Names: | olfactomedin 1 |
| NCBI Official Symbol: | OLFM1 |
| NCBI Official Synonym Symbols: | AMY; NOE1; OlfA; NOELIN1 |
| NCBI Protein Information: | noelin; pancortin 1; olfactomedin-1; neuroblastoma protein; olfactomedin related ER localized protein; neuronal olfactomedin-related ER localized protein |
| UniProt Protein Name: | Noelin |
| UniProt Synonym Protein Names: | Neuronal olfactomedin-related ER localized protein; Olfactomedin-1 |
| Protein Family: | Noelin |
| UniProt Gene Name: | OLFM1 |
| UniProt Entry Name: | NOE1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using OLFM1 antibody (CAB0261) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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