Anti-Neurotrimin Antibody (CAB8994)

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SKU:
CAB8994
Product type:
Antibody
Application:
WB
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Frequently bought together:

Description

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Antibody Name:Anti-Neurotrimin Antibody
Antibody SKU:CAB8994
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-316 of human NTM (NP_001137531.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HT-1080, SW480, Mouse eye, Mouse liver, Rat eye
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-316 of human NTM (NP_001137531.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:PVRS GDAT FPKA MDNV TVRQ GESA TLRC TIDN RVTR VAWL NRST ILYA GNDK WCLD PRVV LLSN TQTQ YSIE IQNV DVYD EGPY TCSV QTDN HPKT SRVH LIVQ VSPK IVEI SSDI SINE GNNI SLTC IATG RPEP TVTW RHIS PKAV GFVS EDEY LEIQ GITR EQSG DYEC SASN DVAA PVVR RVKV TVNY PPYI SEAK GTGV PVGQ KGTL QCEA SAVP SAEF QWYK DDKR LIEG KKGV KVEN RPFL SKLI FFNV SEHD YGNY TCVA SNKL GHTN ASIM LFGE TVL
Gene ID:50863
Uniprot:Q9P121
Cellular Location:Cell membrane, GPI-anchor, Lipid-anchor
Calculated MW:34kDa/37kDa/39kDa
Observed MW:38kDa
Synonyms:NTM, HNT, IGLON2, NTRI
Background:This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:NT: Neural cell adhesion molecule. Belongs to the immunoglobulin superfamily. IgLON family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cell adhesion; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 11q25

Cellular Component: neuron projection; cell surface; cell soma; plasma membrane; intercellular junction

Molecular Function:protein binding

Biological Process: cell-cell adhesion; regulation of neurogenesis; neuron recognition; cell adhesion

NCBI Summary:This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]
UniProt Code:Q9P121
NCBI GenInfo Identifier:7705413
NCBI Gene ID:50863
NCBI Accession:
UniProt Related Accession:Q9P121
Molecular Weight:
NCBI Full Name:neurotrimin isoform 1
NCBI Synonym Full Names:neurotrimin
NCBI Official Symbol:NTM  
NCBI Official Synonym Symbols:HNT; NTRI; CEPU-1; IGLON2  
NCBI Protein Information:neurotrimin
UniProt Protein Name:Neurotrimin
UniProt Synonym Protein Names:IgLON family member 2
Protein Family:Neurotrimin
UniProt Gene Name:NTM  
UniProt Entry Name:NTRI_HUMAN
Anti-Neurotrimin Polyclonal Antibody (CAB8994)Western blot analysis of extracts of various cell lines, using NTM antibody (CAB8994) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.

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