Anti-INPP5A Antibody (CAB3302)
- SKU:
- CAB3302
- Product type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-INPP5A Antibody |
| Antibody SKU: | CAB3302 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-200 of human INPP5A (NP_005530.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse heart, Mouse lung, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-200 of human INPP5A (NP_005530.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TAVL LVTA NVGS LFDD PENL QKNW LREF YQVV HTHK PHFM ALHC QEFG GKNY EASM SHVD KFVK ELLS SDAM KEYN RARV YLDE NYKS QEHF TALG SFYF LHES LKNI YQFD FKAK KYRK VAGK EIYS DTLE STPM LEKE KFPQ DYFP ECKW SRKG FIRT RWCI ADCA FDLV NIHL FHDA SNLV AWET SPS |
| Gene ID: | 3632 |
| Uniprot: | Q14642 |
| Cellular Location: | Lipid-anchor, Membrane |
| Calculated MW: | 47kDa |
| Observed MW: | 40kDa |
| Synonyms: | INPP5A, 5PTASE |
| Background: | The protein encoded by this gene is a membrane-associated type I inositol 1, 4, 5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1, 4, 5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. |
| UniProt Protein Function: | INPP5A: Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction. Belongs to the inositol 1,4,5-trisphosphate 5- phosphatase type I family. |
| UniProt Protein Details: | Protein type:Carbohydrate Metabolism - inositol phosphate; EC 3.1.3.56; Phosphatase (non-protein) Chromosomal Location of Human Ortholog: 10q26.3 Cellular Component: plasma membrane Molecular Function:PH domain binding; protein binding Biological Process: inositol phosphate metabolic process |
| NCBI Summary: | The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q14642 |
| NCBI GenInfo Identifier: | 3122245 |
| NCBI Gene ID: | 3632 |
| NCBI Accession: | Q14642.1 |
| UniProt Secondary Accession: | Q14642,Q14640, Q5JSF1, D3DXI3, |
| UniProt Related Accession: | Q14642 |
| Molecular Weight: | 47,820 Da |
| NCBI Full Name: | Type I inositol 1,4,5-trisphosphate 5-phosphatase |
| NCBI Synonym Full Names: | inositol polyphosphate-5-phosphatase A |
| NCBI Official Symbol: | INPP5A |
| NCBI Official Synonym Symbols: | 5PTASE |
| NCBI Protein Information: | type I inositol 1,4,5-trisphosphate 5-phosphatase |
| UniProt Protein Name: | Type I inositol 1,4,5-trisphosphate 5-phosphatase |
| Protein Family: | Type I inositol 1,4,5-trisphosphate 5-phosphatase |
| UniProt Gene Name: | INPP5A |
| UniProt Entry Name: | I5P1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using INPP5A antibody (CAB3302) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
