Anti-IGSF3 Antibody (CAB7689)
- SKU:
- CAB7689
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-IGSF3 Antibody |
| Antibody SKU: | CAB7689 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-562 of human IGSF3 (NP_001007238.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: | 293T, MCF7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-562 of human IGSF3 (NP_001007238.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KVAK ESDS VFVL KIYH LRQE DSGK YNCR VTER EKTV TGEF IDKE SKRP KNIP IIVL PLKS SISV EVAS NASV ILEG EDLR FSCS VRTA GRPQ GRFS VIWQ LVDR QNRR SNIM WLDR DGTV QPGS SYWE RSSF GGVQ MEQV QPNS FSLG IFNS RKED EGQY ECHV TEWV RAVD GEWQ IVGE RRAS TPIS ITAL EMGF AVTA ISRT PGVT YSDS F |
| Gene ID: | 3321 |
| Uniprot: | O75054 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 135kDa/137kDa |
| Observed MW: | 125kDa |
| Synonyms: | IGSF3, EWI-3, LCDD, V8 |
| Background: | The protein encoded by this gene is an immunoglobulin-like membrane protein containing several V-type Ig-like domains. A mutation in this gene has been associated with bilateral nasolacrimal duct obstruction (LCDD). |
| UniProt Protein Function: | IGSF3: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Immunoglobulin superfamily; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p13.1 Cellular Component: cell surface; integral to membrane; plasma membrane Biological Process: cell surface receptor linked signal transduction; lacrimal gland development Disease: Lacrimal Duct Defect |
| NCBI Summary: | The protein encoded by this gene is an immunoglobulin-like membrane protein containing several V-type Ig-like domains. A mutation in this gene has been associated with bilateral nasolacrimal duct obstruction (LCDD). [provided by RefSeq, Jun 2016] |
| UniProt Code: | O75054 |
| NCBI GenInfo Identifier: | 172046061 |
| NCBI Gene ID: | 3321 |
| NCBI Accession: | O75054.3 |
| UniProt Secondary Accession: | O75054,A6NJZ6, A6NMC7, |
| UniProt Related Accession: | O75054 |
| Molecular Weight: | 135kDa |
| NCBI Full Name: | Immunoglobulin superfamily member 3 |
| NCBI Synonym Full Names: | immunoglobulin superfamily member 3 |
| NCBI Official Symbol: | IGSF3 |
| NCBI Official Synonym Symbols: | V8; LCDD; EWI-3 |
| NCBI Protein Information: | immunoglobulin superfamily member 3 |
| UniProt Protein Name: | Immunoglobulin superfamily member 3 |
| UniProt Synonym Protein Names: | Glu-Trp-Ile EWI motif-containing protein 3; EWI-3 |
| Protein Family: | Immunoglobulin superfamily |
| UniProt Gene Name: | IGSF3 |
 | Western blot analysis of extracts of various cell lines, using IGSF3 Antibody (CAB7689) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human prostate using IGSF3 antibody (CAB7689) (40x lens). |
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