Anti-HS1BP3 Antibody (CAB8250)
- SKU:
- CAB8250
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | HS1BP3 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB8250 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HS1BP3 (NP_071905.3). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, Mouse liver, Mouse kidney, Mouse heart, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HS1BP3 (NP_071905.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MQSP AVLV TSRR LQNA HTGL DLTV PQHQ EVRG KMMS GHVE YQIL VVTR LAAF KSAK HRPE DVVQ FLVS KKYS EIEE FYQK LSSR YAAA SLPP LPRK VLFV GESD IRER RAVF NEIL RCVS KDAE LAGS PELL EFLG TRSP GAAG LTSR DSSV LDGT DSQT GNDE EAFD FFEE QDQV AEEG PPVQ SLKG EDAE ESLE EEEA |
| Gene ID: | 64342 |
| Uniprot: | Q53T59 |
| Cellular Location: | |
| Calculated MW: | 42kDa |
| Observed MW: | 55kDa |
| Synonyms: | HS1BP3, ETM2, HS1-BP3 |
| Background: | The protein encoded by this gene shares similarity with mouse Hs1bp3, an Hcls1/Hs1-interacting protein that may be involved in lymphocyte activation. |
| UniProt Protein Function: | HS1BP3: May be a modulator of IL-2 signaling. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2p24.1 Molecular Function:phosphoinositide binding |
| NCBI Summary: | Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q53T59 |
| NCBI GenInfo Identifier: | 12652984 |
| NCBI Gene ID: | 158 |
| NCBI Accession: | BC000253 |
| UniProt Secondary Accession: | Q53T59,Q86VC2, Q8N367, B2RAW2, D6W529, |
| UniProt Related Accession: | P30566 |
| Molecular Weight: | 42,780 Da |
| NCBI Full Name: | Homo sapiens adenylosuccinate lyase, mRNA |
| NCBI Synonym Full Names: | adenylosuccinate lyase |
| NCBI Official Symbol: | ADSL |
| NCBI Official Synonym Symbols: | ASL; AMPS; ASASE |
| NCBI Protein Information: | adenylosuccinate lyase; adenylosuccinase |
| UniProt Protein Name: | HCLS1-binding protein 3 |
| UniProt Synonym Protein Names: | HS1-binding protein 3; HSP1BP-3 |
| Protein Family: | HCLS1-binding protein |
| UniProt Gene Name: | HS1BP3 |
| UniProt Entry Name: | H1BP3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using HS1BP3 antibody (CAB8250) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
 | Immunohistochemistry of paraffin-embedded human stomach using HS1BP3 antibody (CAB8250) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat kidney using HS1BP3 antibody (CAB8250) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of U2OS cells using HS1BP3 antibody (CAB8250) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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