Anti-HRH4 Antibody (CAB10151)
- SKU:
- CAB10151
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-HRH4 Antibody |
| Antibody SKU: | CAB10151 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 194-304 of human HRH4 (NP_067637.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:4000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | LO2, 293T, Raji, HT-29, Mouse liver, Mouse pancreas, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 194-304 of human HRH4 (NP_067637.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NMNI YWSL WKRD HLSR CQSH PGLT AVSS NICG HSFR GRLS SRRS LSAS TEVP ASFH SERQ RRKS SLMF SSRT KMNS NTIA SKMG SFSQ SDSV ALHQ REHV ELLR ARRL AKS |
| Gene ID: | 59340 |
| Uniprot: | Q9H3N8 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 34kDa/44kDa |
| Observed MW: | 44kDa |
| Synonyms: | HRH4, AXOR35, BG26, GPCR105, GPRv53, H4, H4R, HH4R |
| Background: | Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | H4R: The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist). Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR Chromosomal Location of Human Ortholog: 18q11.2 Cellular Component: plasma membrane; synapse Molecular Function:G-protein coupled acetylcholine receptor activity Biological Process: inflammatory response; muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway; muscarinic acetylcholine receptor, phospholipase C activating pathway; synaptic transmission, cholinergic |
| NCBI Summary: | Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
| UniProt Code: | Q9H3N8 |
| NCBI GenInfo Identifier: | 14194819 |
| NCBI Gene ID: | 59340 |
| NCBI Accession: | Q9H3N8.2 |
| UniProt Secondary Accession: | Q9H3N8,Q4G0I6, Q9GZQ0, B0YJ19, B2KJ48, |
| UniProt Related Accession: | Q9H3N8 |
| Molecular Weight: | 34,497 Da |
| NCBI Full Name: | Histamine H4 receptor |
| NCBI Synonym Full Names: | histamine receptor H4 |
| NCBI Official Symbol: | HRH4 |
| NCBI Official Synonym Symbols: | H4; H4R; BG26; HH4R; AXOR35; GPRv53; GPCR105 |
| NCBI Protein Information: | histamine H4 receptor |
| UniProt Protein Name: | Histamine H4 receptor |
| UniProt Synonym Protein Names: | AXOR35; G-protein coupled receptor 105; GPRv53; Pfi-013; SP9144 |
| Protein Family: | Histamine H4 receptor |
| UniProt Gene Name: | HRH4 |
| UniProt Entry Name: | HRH4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using HRH4 antibody (CAB10151) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
Related Products
Rat Histamine Receptor H4 / HRH4 ELISA Kit
Human HRH4(Histamine Receptor H4) ELISA Kit
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
