Anti-Guanylyl Cyclase beta 1 (GUCY1B3) Antibody (CAB3687)
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- SKU:
- CAB3687
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GC-S-beta-1
- GC-SB3
- GUC1B3
- GUCB3
- GUCSB3
- GUCY1B1
Frequently bought together:
Description
| Product Name: | Guanylyl Cyclase beta 1 (GUCY1B3) Rabbit mAb |
| Product Code: | CAB3687 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | GC-S-beta-1, GC-SB3, GUC1B3, GUCB3, GUCSB3, GUCY1B1 |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Guanylyl Cyclase beta 1 (GUCY1B3) (GUCY1B3) |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, Mouse lung, Mouse brain, Mouse heart, Rat brain |
| Immunogen: | A synthesized peptide derived from human Guanylyl Cyclase beta 1 (GUCY1B3) (GUCY1B3) |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2983 |
| Uniprot: | Q02153 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 71kDa |
| Observed MW: | 71kDa |
| UniProt Protein Function: | GUCY1B3: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Heterodimer of an alpha and a beta chain. 2 isoforms of the human protein are produced by alternative splicing |
| UniProt Protein Details: | Protein type:Receptor, misc.; Guanylyl cyclase; Lyase; Nucleotide Metabolism - purine; EC 4.6.1.2 Chromosomal Location of Human Ortholog: 4q31.3-q33 Cellular Component: guanylate cyclase complex, soluble; intracellular membrane-bound organelle; cytoplasm Molecular Function:guanylate cyclase activity; GTP binding; protein heterodimerization activity; metal ion binding; heme binding; Hsp90 protein binding; receptor activity Biological Process: cGMP biosynthetic process; blood circulation; blood coagulation; nitric oxide mediated signal transduction |
| NCBI Summary: | This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
| UniProt Code: | Q02153 |
| NCBI GenInfo Identifier: | 399328 |
| NCBI Gene ID: | 2983 |
| NCBI Accession: | Q02153.1 |
| UniProt Secondary Accession: | Q02153,Q86WY5, B7Z426, |
| UniProt Related Accession: | Q02153 |
| Molecular Weight: | 619 |
| NCBI Full Name: | Guanylate cyclase soluble subunit beta-1 |
| NCBI Synonym Full Names: | guanylate cyclase 1, soluble, beta 3 |
| NCBI Official Symbol: | GUCY1B3 |
| NCBI Official Synonym Symbols: | GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B1; GC-S-beta-1 |
| NCBI Protein Information: | guanylate cyclase soluble subunit beta-1; GCS-beta-1; GCS-beta-3; soluble guanylate cyclase small subunit; guanylate cyclase soluble subunit beta-3 |
| UniProt Protein Name: | Guanylate cyclase soluble subunit beta-1 |
| UniProt Synonym Protein Names: | Guanylate cyclase soluble subunit beta-3; GCS-beta-3; Soluble guanylate cyclase small subunit |
| Protein Family: | Guanylate cyclase soluble |
| UniProt Gene Name: | GUCY1B3 |
| UniProt Entry Name: | GCYB1_HUMAN |
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