Anti-GTF3C3 Antibody (CAB18405)
- SKU:
- CAB18405
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Antibody Name: | Anti-GTF3C3 Antibody |
Antibody SKU: | CAB18405 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human GTF3C3. |
Application: | WB IHC IF |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | HepG2, HeLa, 293T, RAW264.7, NIH/3T3, Mouse lung |
Immunogen: | Recombinant protein of human GTF3C3. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 9330 |
Uniprot: | Q9Y5Q9 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | 101kDa |
Synonyms: | TFIIIC102, TFIIICgamma, TFiiiC2-102, GTF3C3 |
Background: |
UniProt Protein Function: | GTF3C3: Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 2q33.1 Cellular Component: nuclear membrane; nucleolus; nucleoplasm; nucleus; transcription factor TFIIIC complex Molecular Function:DNA binding; protein binding Biological Process: 5S class rRNA transcription; transcription from RNA polymerase III promoter; transcription, DNA-dependent; tRNA transcription from RNA polymerase III promoter |
NCBI Summary: | The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
UniProt Code: | Q9Y5Q9 |
NCBI GenInfo Identifier: | 47606223 |
NCBI Gene ID: | 9330 |
NCBI Accession: | Q9Y5Q9.1 |
UniProt Secondary Accession: | Q9Y5Q9,Q4ZG48, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97 |
UniProt Related Accession: | Q9Y5Q9 |
Molecular Weight: | 47,258 Da |
NCBI Full Name: | General transcription factor 3C polypeptide 3 |
NCBI Synonym Full Names: | general transcription factor IIIC subunit 3 |
NCBI Official Symbol: | GTF3C3 |
NCBI Official Synonym Symbols: | TFIIIC102; TFIIICgamma; TFiiiC2-102 |
NCBI Protein Information: | general transcription factor 3C polypeptide 3 |
UniProt Protein Name: | General transcription factor 3C polypeptide 3 |
UniProt Synonym Protein Names: | Transcription factor IIIC 102 kDa subunit; TFIIIC 102 kDa subunit; TFIIIC102; Transcription factor IIIC subunit gamma; TF3C-gamma |
Protein Family: | General transcription factor 3C polypeptide |
UniProt Gene Name: | GTF3C3 |
UniProt Entry Name: | TF3C3_HUMAN |