Anti-GLP2R Antibody (CAB6602)
- SKU:
- CAB6602
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-GLP2R Antibody |
| Antibody SKU: | CAB6602 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human GLP2R (NP_004237.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | NCI-H460, HeLa, HepG2, Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human GLP2R (NP_004237.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MKLG SSRA GPGR GSAG LLPG VHEL PMGI PAPW GTSP LSFH RKCS LWAP GRPF LTLV LLVS IKQV TGSL LEET TRKW AQYK QACL RDLL KEPS GIFC NGTF DQYV CWPH SSPG NVSV PCPS YLPW WSEE SSGR AYRH CLAQ GTWQ TIEN ATDI WQDD SECS ENHS FKQN VDRY ALLS TLQL |
| Gene ID: | 9340 |
| Uniprot: | O95838 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 63kDa |
| Observed MW: | 63kDa |
| Synonyms: | GLP2R |
| Background: | This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. |
| UniProt Protein Function: | GLP2R: This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral Chromosomal Location of Human Ortholog: 17p13.3 Cellular Component: plasma membrane; integral to membrane Molecular Function:G-protein coupled receptor activity; glucagon receptor activity Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; positive regulation of cell proliferation |
| NCBI Summary: | This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014] |
| UniProt Code: | O95838 |
| NCBI GenInfo Identifier: | 12230071 |
| NCBI Gene ID: | 9340 |
| NCBI Accession: | O95838.1 |
| UniProt Secondary Accession: | O95838,Q4VAT3, |
| UniProt Related Accession: | O95838 |
| Molecular Weight: | Calculated: 63kDaObserved: 63kDa |
| NCBI Full Name: | Glucagon-like peptide 2 receptor |
| NCBI Synonym Full Names: | glucagon-like peptide 2 receptor |
| NCBI Official Symbol: | GLP2R |
| NCBI Protein Information: | glucagon-like peptide 2 receptor; GLP-2 receptor |
| UniProt Protein Name: | Glucagon-like peptide 2 receptor |
| Protein Family: | Glucagon-like peptide 2 receptor |
| UniProt Gene Name: | GLP2R |
| UniProt Entry Name: | GLP2R_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GLP2R antibody (CAB6602) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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