Anti-ENC1 Antibody (CAB10257)
- SKU:
- CAB10257
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-ENC1 Antibody |
| Antibody SKU: | CAB10257 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ENC1 (NP_003624.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, U-87MG, SW480, MCF7, HT-1080, Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ENC1 (NP_003624.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSVS VHEN RKSR ASSG SINI YLFH KSSY ADSV LTHL NLLR QQRL FTDV LLHA GNRT FPCH RAVL AACS RYFE AMFS GGLK ESQD SEVN FDNS IHPE VLEL LLDY AYSS RVII NEEN AESL LEAG DMLE FQDI RDAC AEFL EKNL HPTN CLGM LLLS DAHQ CTKL YELS WRMC LSNF QTIR KNED FLQL PQDM VVQL LSSE ELET EDER LVYE SAIN WISY DLKK RYCY LPEL LQTV RLAL LPAI YLME NVAM EELI TKQR KSKE IVEE AI |
| Gene ID: | 8507 |
| Uniprot: | O14682 |
| Cellular Location: | Cytoplasm, Nucleus matrix, cytoskeleton |
| Calculated MW: | 57kDa/66kDa |
| Observed MW: | 66kDa |
| Synonyms: | ENC1, CCL28, ENC-1, KLHL35, KLHL37, NRPB, PIG10, TP53I10 |
| Background: | This gene encodes a member of the kelch-related family of actin-binding proteins. The encoded protein plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2, and expression of this gene may play a role in malignant transformation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| UniProt Protein Function: | Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin-mediated proteasomal degradation mechanism. |
| NCBI Summary: | This gene encodes a member of the kelch-related family of actin-binding proteins. The encoded protein plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2, and expression of this gene may play a role in malignant transformation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012] |
| UniProt Code: | O14682 |
| NCBI GenInfo Identifier: | 12644050 |
| NCBI Gene ID: | 8507 |
| NCBI Accession: | O14682.2 |
| UniProt Secondary Accession: | O14682,O75464, Q9UPG9, B4DHJ1, E9PFU0, |
| UniProt Related Accession: | O14682 |
| Molecular Weight: | 66kDa |
| NCBI Full Name: | Ectoderm-neural cortex protein 1 |
| NCBI Synonym Full Names: | ectodermal-neural cortex 1 |
| NCBI Official Symbol: | ENC1 |
| NCBI Official Synonym Symbols: | NRPB; CCL28; ENC-1; PIG10; KLHL35; KLHL37; TP53I10 |
| NCBI Protein Information: | ectoderm-neural cortex protein 1 |
| UniProt Protein Name: | Ectoderm-neural cortex protein 1 |
| UniProt Synonym Protein Names: | Kelch-like protein 37; Nuclear matrix protein NRP/B; p53-induced gene 10 protein |
| Protein Family: | Ectoderm-neural cortex protein |
| UniProt Gene Name: | ENC1 |
 | Western blot analysis of extracts of various cell lines, using ENC1 antibody (CAB10257) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 40s. |
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