Anti-ELMOD3 Antibody (CAB7532)
- SKU:
- CAB7532
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-ELMOD3 Antibody |
| Antibody SKU: | CAB7532 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 290-381 of human ELMOD3 (NP_001128493.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 290-381 of human ELMOD3 (NP_001128493.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ATFL HLAH VWRT QRKT ISDS GFVL KELE VLAK KSPR RLLK TLEL YLAR VSKG QASL LGAQ KCYG PEAP PFKD LTFT GESD LQSH SSEG VWLI |
| Gene ID: | 84173 |
| Uniprot: | Q96FG2 |
| Cellular Location: | Cell projection, Cytoplasm, cytoskeleton, kinocilium, stereocilium |
| Calculated MW: | 18kDa/20kDa/28kDa/43kDa/44kDa |
| Observed MW: | 38/43kDa |
| Synonyms: | ELMOD3, DFNB88, LST3, RBED1, RBM29 |
| Background: | This gene encodes a member of the engulfment and cell motility family of GTPase-activating proteins that regulate Arf GTPase proteins. Members of this family are defined by a conserved engulfment and cell motility domain. In rat cochlea, the encoded protein is found in stereocilia, kinocilia and cuticular plate of developing hair cells suggesting a function for this protein in cochlear sensory cells. An allelic variant of this family has been associated with autosomal recessive nonsyndromic deafness-88 in humans. Alternative splicing results in multiple transcript variants. |
| UniProt Code: | Q96FG2 |
| NCBI GenInfo Identifier: | 203098474 |
| NCBI Gene ID: | 84173 |
| NCBI Accession: | NP_001128493.1 |
| UniProt Secondary Accession: | Q96FG2,Q91YP6, Q5XIQ2, |
| UniProt Related Accession: | Q96FG2 |
| Molecular Weight: | 43,046 Da |
| NCBI Full Name: | ELMO domain-containing protein 3 isoform b |
| NCBI Synonym Full Names: | ELMO/CED-12 domain containing 3 |
| NCBI Official Symbol: | ELMOD3 |
| NCBI Official Synonym Symbols: | LST3; RBED1; RBM29; DFNB88 |
| NCBI Protein Information: | ELMO domain-containing protein 3; C330008I15Rik; RNA-binding protein 29; RNA binding motif protein 29; RNA-binding motif protein 29; deafness, autosomal recessive 88; organic anion transporter LST-3b; RNA binding motif and ELMO domain 1; RNA binding motif |
| UniProt Protein Name: | ELMO domain-containing protein 3 |
| UniProt Synonym Protein Names: | RNA-binding motif and ELMO domain-containing protein 1; RNA-binding motif protein 29; RNA-binding protein 29 |
| UniProt Gene Name: | ELMOD3 |
| UniProt Entry Name: | ELMD3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ELMOD3 antibody (CAB7532) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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