Anti-DLGAP2 Antibody (CAB13818)
- SKU:
- CAB13818
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-DLGAP2 Antibody |
| Antibody SKU: | CAB13818 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 550-800 of human DLGAP2 (NP_004736.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-87MG, 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 550-800 of human DLGAP2 (NP_004736.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TAQS STES TQDA YQDS RAQR MSPW PQDS RGLY NSTD SLDS NKAM NLAL ETAA AQRH LPES QSSS VRTS DKAI LVSK AEEL LKSR CSSI GIQD SEFP EHQP YPRS DVET ATDS DTES RGLR EYHS VGVQ VEDE KRHG RFKR SNSV TAAV QADL ELEG FPGH ITTE DKGL QFGS SFQR HSEP STPT QYSA VRTV RTQG LFSY REDY RTQV DTST LPPP DPWL EPAI DTVE TGRM SPCR RDGS WFLK LLHA ETK |
| Gene ID: | 9228 |
| Uniprot: | Q9P1A6 |
| Cellular Location: | Cell junction, Cell membrane, Peripheral membrane protein, postsynaptic cell membrane, postsynaptic density, synapse |
| Calculated MW: | 108kDa/115kDa/117kDa |
| Observed MW: | 117kDa |
| Synonyms: | DLGAP2, C8orf68, DAP2, ERICH1-AS1, SAPAP2 |
| Background: | The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. |
| UniProt Protein Function: | SAPAP2: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Belongs to the SAPAP family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Kinase, other Chromosomal Location of Human Ortholog: 8p23 Cellular Component: postsynaptic membrane; postsynaptic density; neurofilament; cell junction Molecular Function:protein binding Biological Process: nerve-nerve synaptic transmission |
| NCBI Summary: | The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2014] |
| UniProt Code: | Q9P1A6 |
| NCBI GenInfo Identifier: | 160395585 |
| NCBI Gene ID: | 9228 |
| NCBI Accession: | Q9P1A6.4 |
| UniProt Secondary Accession: | Q9P1A6,O14488, O14664, Q9P1A7, A1QCF8, A1QCF9, A5D8Y2 |
| UniProt Related Accession: | Q9P1A6 |
| Molecular Weight: | |
| NCBI Full Name: | Disks large-associated protein 2 |
| NCBI Synonym Full Names: | discs, large (Drosophila) homolog-associated protein 2 |
| NCBI Official Symbol: | DLGAP2 |
| NCBI Official Synonym Symbols: | DAP2; SAPAP2 |
| NCBI Protein Information: | disks large-associated protein 2; PSD-95/SAP90-binding protein 2; discs large-associated protein 2; SAP90/PSD-95-associated protein 2 |
| UniProt Protein Name: | Disks large-associated protein 2 |
| UniProt Synonym Protein Names: | PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2; SAPAP2 |
| Protein Family: | Disks large-associated protein |
| UniProt Gene Name: | DLGAP2 |
| UniProt Entry Name: | DLGP2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DLGAP2 antibody (CAB13818) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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