Anti-DEFA5 Antibody (CAB18208)
- SKU:
- CAB18208
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Antibody Name: | Anti-DEFA5 Antibody |
| Antibody SKU: | CAB18208 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human DEFA5. |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant protein of human DEFA5. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1670 |
| Uniprot: | Q01523 |
| Cellular Location: | |
| Calculated MW: | 10kDa |
| Observed MW: | Refer to figures |
| Synonyms: | DEF5, HD-5, DEFA5 |
| Background: | Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. |
| UniProt Protein Function: | Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing. |
| NCBI Summary: | Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. [provided by RefSeq, Oct 2014] |
| UniProt Code: | Q01523 |
| NCBI GenInfo Identifier: | 399353 |
| NCBI Gene ID: | 1670 |
| NCBI Accession: | Q01523.1 |
| UniProt Secondary Accession: | Q01523,Q3KNV2, A0JDY6, |
| UniProt Related Accession: | Q01523 |
| Molecular Weight: | 10,071 Da |
| NCBI Full Name: | Defensin-5 |
| NCBI Synonym Full Names: | defensin alpha 5 |
| NCBI Official Symbol: | DEFA5 |
| NCBI Official Synonym Symbols: | DEF5; HD-5 |
| NCBI Protein Information: | defensin-5 |
| UniProt Protein Name: | Defensin-5 |
| UniProt Synonym Protein Names: | Defensin, alpha 5; HD5(20-94) |
| UniProt Gene Name: | DEFA5 |
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Human Defensin-5 (DEFA5) ELISA Kit
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