Anti-CSRP1 Antibody (CAB1071)
- SKU:
- CAB1071
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-CSRP1 Antibody |
| Antibody SKU: | CAB1071 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IP RIP |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human CSRP1 (NP_004069.1). |
| Application: | WB IP RIP |
| Recommended Dilution: | WB 1:500 - 1:2000 IP 1:50 - 1:200 RIP 1:20 - 1:50 |
| Reactivity: | Human, Mouse |
| Positive Samples: | A-549, BT-474, HeLa, Mouse lung, Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human CSRP1 (NP_004069.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MPNW GGGK KCGV CQKT VYFA EEVQ CEGN SFHK SCFL CMVC KKNL DSTT VAVH GEEI YCKS CYGK KYGP KGYG YGQG AGTL STDK GESL GIKH EEAP GHRP TTNP NASK FAQK IGGS ERCP RCSQ AVYA AEKV IGAG KSWH KACF RCAK CGKG LEST TLAD KDGE IYCK GCYA KNFG PKGF GFGQ GAGA LVHS E |
| Gene ID: | 1465 |
| Uniprot: | P21291 |
| Cellular Location: | Nucleus |
| Calculated MW: | 20kDa |
| Observed MW: | 21kDa |
| Synonyms: | CSRP1, CRP, CRP1, CSRP, CYRP, D1S181E, HEL-141, HEL-S-286 |
| Background: | This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Alternatively spliced transcript variants have been described. |
| UniProt Protein Function: | CSRP1: a LIM protein. Involved in the noncanonical Wnt pathway, which coordinates cell behaviors during dynamic morphogenetic movements of tissues and organs. Interacts with Dishevelled 2 (Dvl2) and Diversin (Div) in zebrafish. Displays coordinate serum induction with c-myc. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 1q32 Cellular Component: focal adhesion; nucleus Molecular Function:zinc ion binding |
| NCBI Summary: | This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010] |
| UniProt Code: | P21291 |
| NCBI GenInfo Identifier: | 118161 |
| NCBI Gene ID: | 1465 |
| NCBI Accession: | P21291.3 |
| UniProt Secondary Accession: | P21291,Q5U0J2, A8K268, |
| UniProt Related Accession: | P21291 |
| Molecular Weight: | 193 |
| NCBI Full Name: | Cysteine and glycine-rich protein 1 |
| NCBI Synonym Full Names: | cysteine and glycine-rich protein 1 |
| NCBI Official Symbol: | CSRP1 |
| NCBI Official Synonym Symbols: | CRP; CRP1; CSRP; CYRP; D1S181E; HEL-141 |
| NCBI Protein Information: | cysteine and glycine-rich protein 1; LIM-domain protein; cysteine-rich protein 1; epididymis luminal protein 141 |
| UniProt Protein Name: | Cysteine and glycine-rich protein 1 |
| UniProt Synonym Protein Names: | Cysteine-rich protein 1; CRP; CRP1; Epididymis luminal protein 141; HEL-141 |
| Protein Family: | Cysteine and glycine-rich protein |
| UniProt Gene Name: | CSRP1 |
| UniProt Entry Name: | CSRP1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CSRP1 Antibody (CAB1071) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). |
 | Immunoprecipitation analysis of 200ug extracts of HepG2 cells using 1ug CSRP1 antibody (CAB1071). Western blot was performed from the immunoprecipitate using CSRP1 antibody (CAB1071) at a dilition of 1:1000. |
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