Anti-CSRNP1 Antibody (CAB7130)
- SKU:
- CAB7130
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| Antibody Name: | Anti-CSRNP1 Antibody |
| Antibody SKU: | CAB7130 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CSRNP1 (NP_149016.2). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CSRNP1 (NP_149016.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MTGL LKRK FDQL DEDN SSVS SSSS SSGC QSRS CSPS SSVS RAWD SEEE GPWD QMPL PDRD FCGP RSFT PLSI LKRA RRER PGRV AFDG ITVF YFPR CQGF TSVP SRGG CTLG MALR HSAC RRFS LAEF AQEQ ARAR HEKL RQRL KEEK LEML QWKL SAAG VPQA EAGL PPVV DAID DASV EEDL AVAV AGGR LEEV SFLQ |
| Gene ID: | 64651 |
| Uniprot: | Q96S65 |
| Cellular Location: | Nucleus |
| Calculated MW: | 63kDa |
| Observed MW: | Refer to figures |
| Synonyms: | CSRNP1, AXUD1, CSRNP-1, FAM130B, TAIP-3, URAX1 |
| Background: | This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | AXUD1: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May have a tumor-suppressor function. May play a role in apoptosis. Belongs to the AXUD1 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3p22 Cellular Component: nucleus Molecular Function:sequence-specific DNA binding; transcription factor activity Biological Process: transcription, DNA-dependent; apoptosis; skeletal morphogenesis; platelet-derived growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; palate development; post-embryonic development |
| NCBI Summary: | This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96S65 |
| NCBI GenInfo Identifier: | 308153432 |
| NCBI Gene ID: | 64651 |
| NCBI Accession: | Q96S65.2 |
| UniProt Secondary Accession: | Q96S65,Q69YY5, |
| UniProt Related Accession: | Q96S65 |
| Molecular Weight: | 589 |
| NCBI Full Name: | Cysteine/serine-rich nuclear protein 1 |
| NCBI Synonym Full Names: | cysteine-serine-rich nuclear protein 1 |
| NCBI Official Symbol: | CSRNP1 |
| NCBI Official Synonym Symbols: | AXUD1; URAX1; TAIP-3; CSRNP-1; FAM130B |
| NCBI Protein Information: | cysteine/serine-rich nuclear protein 1; AXIN1 up-regulated 1; axin-1 up-regulated gene 1 protein; TGF-beta induced apoptosis protein 3; TGF-beta-induced apoptosis protein 3 |
| UniProt Protein Name: | Cysteine/serine-rich nuclear protein 1 |
| UniProt Synonym Protein Names: | Axin-1 up-regulated gene 1 protein; Protein URAX1; TGF-beta-induced apoptosis protein 3; TAIP-3 |
| Protein Family: | Cysteine/serine-rich nuclear protein |
| UniProt Gene Name: | CSRNP1 |
| UniProt Entry Name: | CSRN1_HUMAN |
 | Immunohistochemistry of paraffin-embedded rat kidney using CSRNP1 antibody (CAB7130) at dilution of 1:200 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse brain using CSRNP1 antibody (CAB7130) at dilution of 1:200 (40x lens). |
 | Immunofluorescence analysis of A549 cells using CSRNP1 antibody (CAB7130). |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
