Anti-CPQ Antibody (CAB12062)
- SKU:
- CAB12062
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-CPQ Antibody |
| Antibody SKU: | CAB12062 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CPQ (NP_057218.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, LO2, Mouse kidney, Rat kidney |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CPQ (NP_057218.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MKFL IFAF FGGV HLLS LCSG KAIC KNGI SKRT FEEI KEEI ASCG DVAK AIIN LAVY GKAQ NRSY ERLA LLVD TVGP RLSG SKNL EKAI QIMY QNLQ QDGL |
| Gene ID: | 10404 |
| Uniprot: | Q9Y646 |
| Cellular Location: | Endoplasmic reticulum, Golgi apparatus, Lysosome, Secreted |
| Calculated MW: | 51kDa |
| Observed MW: | 57-60kDa |
| Synonyms: | CPQ, LDP, PGCP |
| Background: | This gene encodes a metallopeptidase that belongs to the peptidase M28 family. The encoded protein may catalyze the cleavage of dipeptides with unsubstituted terminals into amino acids. |
| UniProt Protein Function: | PGCP: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes more efficiently the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in thyroxin hormone liberation from its TG/thyroglobulin precursor. Belongs to the peptidase M28 family. |
| UniProt Protein Details: | Protein type:EC 3.4.17.-; Protease; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 8q22.1 Cellular Component: cytoplasm; endoplasmic reticulum; extracellular space; Golgi apparatus; lysosome Molecular Function:protein homodimerization activity Biological Process: peptide catabolic process; proteolysis; thyroid hormone generation; tissue regeneration |
| NCBI Summary: | This gene encodes a metallopeptidase that belongs to the peptidase M28 family. The encoded protein may catalyze the cleavage of dipeptides with unsubstituted terminals into amino acids. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9Y646 |
| NCBI GenInfo Identifier: | 74735298 |
| NCBI Gene ID: | 10404 |
| NCBI Accession: | Q9Y646.1 |
| UniProt Secondary Accession: | Q9Y646,Q8NBZ1, Q9UNM8, Q9Y5X6, B2RD88, |
| UniProt Related Accession: | Q9Y646 |
| Molecular Weight: | 52kDa |
| NCBI Full Name: | Carboxypeptidase Q |
| NCBI Synonym Full Names: | carboxypeptidase Q |
| NCBI Official Symbol: | CPQ |
| NCBI Official Synonym Symbols: | LDP; PGCP |
| NCBI Protein Information: | carboxypeptidase Q |
| UniProt Protein Name: | Carboxypeptidase Q |
| UniProt Synonym Protein Names: | Lysosomal dipeptidase; Plasma glutamate carboxypeptidase |
| Protein Family: | Carboxypeptidase |
| UniProt Gene Name: | CPQ |
 | Western blot analysis of extracts of various cell lines, using CPQ antibody (CAB12062) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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