Anti-CPB1 Antibody (CAB10486)
- SKU:
- CAB10486
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-CPB1 Antibody |
| Antibody SKU: | CAB10486 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-417 of human CPB1 (NP_001862.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SW620, Mouse pancreas, Mouse liver, Mouse spleen, Rat pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-417 of human CPB1 (NP_001862.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ATGH SYEK YNKW ETIE AWTQ QVAT ENPA LISR SVIG TTFE GRAI YLLK VGKA GQNK PAIF MDCG FHAR EWIS PAFC QWFV REAV RTYG REIQ VTEL LDKL DFYV LPVL NIDG YIYT WTKS RFWR KTRS THTG SSCI GTDP NRNF DAGW CEIG ASRN PCDE TYCG PAAE SEKE TKAL ADFI RNKL SSIK AYLT IHSY SQMM IYPY SYAY KLGE NNAE LNAL AKAT VKEL ASLH GTKY TYGP GATT IYPA AGGS DDWA YDQG IRYS FTFE LRDT GRYG FLLP ESQI RATC EETF LAIK YVAS YVLE HLY |
| Gene ID: | 1360 |
| Uniprot: | P15086 |
| Cellular Location: | Secreted |
| Calculated MW: | 47kDa |
| Observed MW: | 47kDa |
| Synonyms: | CPB1, CPB, PASP, PCPB |
| Background: | Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. |
| UniProt Protein Function: | CPB1: Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; EC 3.4.17.2; Protease Chromosomal Location of Human Ortholog: 3q24 Cellular Component: extracellular region Molecular Function:carboxypeptidase activity; zinc ion binding; metallocarboxypeptidase activity Biological Process: proteolysis |
| NCBI Summary: | Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P15086 |
| NCBI GenInfo Identifier: | 20532382 |
| NCBI Gene ID: | 1360 |
| NCBI Accession: | P15086.4 |
| UniProt Secondary Accession: | P15086,O60834, Q53XJ0, Q96BQ8, |
| UniProt Related Accession: | P15086 |
| Molecular Weight: | 47,368 Da |
| NCBI Full Name: | Carboxypeptidase B |
| NCBI Synonym Full Names: | carboxypeptidase B1 (tissue) |
| NCBI Official Symbol: | CPB1 |
| NCBI Official Synonym Symbols: | CPB; PASP; PCPB |
| NCBI Protein Information: | carboxypeptidase B; pancreas-specific protein; pancreatic carboxypeptidase B; procarboxypeptidase B; protaminase; tissue carboxypeptidase B |
| UniProt Protein Name: | Carboxypeptidase B |
| UniProt Synonym Protein Names: | Pancreas-specific protein; PASP |
| UniProt Gene Name: | CPB1 |
| UniProt Entry Name: | CBPB1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CPB1 antibody (CAB10486) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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