Anti-CECR2 Antibody (CAB10143)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- CAB10143
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Antibody Name: | Anti-CECR2 Antibody |
Antibody SKU: | CAB10143 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-370 of human CECR2 (NP_113601.2). |
Application: | WB |
Recommended Dilution: | WB 1:200 - 1:1000 |
Reactivity: | Mouse, Rat |
Positive Samples: | Mouse liver, Rat liver |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-370 of human CECR2 (NP_113601.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | VQGK SNGE LSLS RESE GQKN VSSI PGKT GKRR GRPP KRKK LQEE ILLS EKQE ENSL ASEP QTRH GSQG PGQG TWWL LCQT EEEW RQVT ESFR ERTS LRER QLYK LLSE DFLP EICN MIAQ KGKR PQRT KAEL HPRW MSDH LSIK PVKQ EETP VLTR IEKQ KRKE EEEE RQIL LAVQ KKEQ EQML KEER KREL EEKV KAVE G |
Gene ID: | 27443 |
Uniprot: | Q9BXF3 |
Cellular Location: | |
Calculated MW: | 58kDa/162kDa/164kDa |
Observed MW: | 164kDa |
Synonyms: | CECR2 |
Background: | This gene encodes a bromodomain-containing protein that is involved in chromatin remodeling, and may additionally play a role in DNA damage response. The encoded protein functions as part of an ATP-dependent complex that is involved in neurulation. This gene is a candidate gene for Cat Eye Syndrome. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | Chromatin reader component of histone-modifying complexes, such as the CERF (CECR2-containing-remodeling factor) complex and ISWI-type complex (PubMed:15640247, PubMed:26365797, PubMed:22464331). It thereby plays a role in various processes during development: required during embryogenesis for neural tube closure and inner ear development. In adults, required for spermatogenesis, via the formation of ISWI-type chromatin complexes. In histone-modifying complexes, CECR2 recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797, PubMed:22464331). May also be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis (PubMed:11827465). |
NCBI Summary: | This gene encodes a bromodomain-containing protein that is involved in chromatin remodeling, and may additionally play a role in DNA damage response. The encoded protein functions as part of an ATP-dependent complex that is involved in neurulation. This gene is a candidate gene for Cat Eye Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
UniProt Code: | Q9BXF3 |
NCBI GenInfo Identifier: | 586798144 |
NCBI Gene ID: | 27443 |
NCBI Accession: | NP_001276976.1 |
UniProt Secondary Accession: | Q9BXF3,Q658Z4, Q96P58, Q9C0C3, A8MS90, A8MX16, |
UniProt Related Accession: | Q9BXF3 |
Molecular Weight: | 58,108 Da |
NCBI Full Name: | cat eye syndrome critical region protein 2 isoform 1 |
NCBI Synonym Full Names: | CECR2, histone acetyl-lysine reader |
NCBI Official Symbol: | CECR2 |
NCBI Protein Information: | cat eye syndrome critical region protein 2 |
UniProt Protein Name: | Cat eye syndrome critical region protein 2 |
Protein Family: | Cat eye syndrome critical region protein |
UniProt Gene Name: | CECR2 |
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