Anti-CCL7 Antibody (CAB16221)
- SKU:
- CAB16221
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-CCL7 Antibody |
| Antibody SKU: | CAB16221 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-99 of human CCL7 (NP_006264.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-99 of human CCL7 (NP_006264.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MKAS AALL CLLL TAAA FSPQ GLAQ PVGI NTST TCCY RFIN KKIP KQRL ESYR RTTS SHCP REAV IFKT KLDK EICA DPTQ KWVQ DFMK HLDK KTQT PKL |
| Gene ID: | 6354 |
| Uniprot: | P80098 |
| Cellular Location: | |
| Calculated MW: | 11kDa |
| Observed MW: | Refer to figures |
| Synonyms: | CCL7, FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7 |
| Background: | This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. |
| UniProt Protein Function: | CCL7: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. Belongs to the intercrine beta (chemokine CC) family. |
| UniProt Protein Details: | Protein type:Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide Chromosomal Location of Human Ortholog: 17q11.2-q12 Cellular Component: extracellular space; extracellular region Molecular Function:heparin binding; CCR1 chemokine receptor binding; CCR2 chemokine receptor binding; chemokine activity Biological Process: cellular calcium ion homeostasis; regulation of cell shape; monocyte chemotaxis; cell-cell signaling; eosinophil chemotaxis; response to gamma radiation; cytoskeleton organization and biogenesis; immune response; chemotaxis; inflammatory response; signal transduction; positive regulation of cell migration |
| NCBI Summary: | This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P80098 |
| NCBI GenInfo Identifier: | 1170890 |
| NCBI Gene ID: | 6354 |
| NCBI Accession: | P80098.3 |
| UniProt Secondary Accession: | P80098,Q569J6, |
| UniProt Related Accession: | P80098 |
| Molecular Weight: | 11,200 Da |
| NCBI Full Name: | C-C motif chemokine 7 |
| NCBI Synonym Full Names: | chemokine (C-C motif) ligand 7 |
| NCBI Official Symbol: | CCL7 |
| NCBI Official Synonym Symbols: | FIC; MARC; MCP3; NC28; MCP-3; SCYA6; SCYA7 |
| NCBI Protein Information: | C-C motif chemokine 7; small-inducible cytokine A7; monocyte chemotactic protein 3; monocyte chemoattractant protein 3; small inducible cytokine A7 (monocyte chemotactic protein 3) |
| UniProt Protein Name: | C-C motif chemokine 7 |
| UniProt Synonym Protein Names: | Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; MCP-3; NC28; Small-inducible cytokine A7 |
| Protein Family: | C-C motif chemokine |
| UniProt Gene Name: | CCL7 |
| UniProt Entry Name: | CCL7_HUMAN |
Related Products
Human MCP3 / CCL7 ELISA Kit
Rat MCP3 / CCL7 ELISA Kit
