Anti-ART1 Antibody (CAB10103)
- SKU:
- CAB10103
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-ART1 Antibody |
| Antibody SKU: | CAB10103 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-295 of human ART1 (NP_004305.2). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | MCF7, B cells, HepG2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-295 of human ART1 (NP_004305.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QSHP ITRR DLFS QEIQ LDMA LASF DDQY AGCA AAMT AALP DLNH TEFQ ANQV YADS WTLA SSQW QERQ ARWP EWSL SPTR PSPP PLGF RDEH GVAL LAYT ANSP LHKE FNAA VREA GRSR AHYL HHFS FKTL HFLL TEAL QLLG SGQR PPRC HQVF RGVH GLRF RPAG PRAT VRLG GFAS ASLK HVAA QQFG EDTF FGIW TCLG APIK GYSF FPGE EEVL IPPF ETFQ VINA SRLA QGPA RIYL RALG KHST YNCE YIKD KKCK SGPC HLDN S |
| Gene ID: | 417 |
| Uniprot: | P52961 |
| Cellular Location: | GPI-anchor, Lipid-anchor, Sarcoplasmic reticulum membrane |
| Calculated MW: | 36kDa |
| Observed MW: | 36kDa |
| Synonyms: | ART1, ART2, ARTC1, CD296, RT6 |
| Background: | ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. |
| UniProt Protein Function: | ART1: Has ADP-ribosyltransferase activity toward GLP1R. Belongs to the Arg-specific ADP-ribosyltransferase family. |
| UniProt Protein Details: | Protein type:Transferase; Membrane protein, GPI anchor; EC 2.4.2.31 Chromosomal Location of Human Ortholog: 11p15 Cellular Component: cell surface; integral to plasma membrane; plasma membrane; sarcoplasmic reticulum membrane Molecular Function:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity Biological Process: innate immune response; protein amino acid ADP-ribosylation |
| NCBI Summary: | ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P52961 |
| NCBI GenInfo Identifier: | 206729882 |
| NCBI Gene ID: | 417 |
| NCBI Accession: | P52961.2 |
| UniProt Secondary Accession: | P52961,Q6NTD2, Q96KT9, |
| UniProt Related Accession: | P52961 |
| Molecular Weight: | 36,335 Da |
| NCBI Full Name: | GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 |
| NCBI Synonym Full Names: | ADP-ribosyltransferase 1 |
| NCBI Official Symbol: | ART1 |
| NCBI Official Synonym Symbols: | RT6; ART2; ARTC1; CD296 |
| NCBI Protein Information: | GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 |
| UniProt Protein Name: | GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 |
| UniProt Synonym Protein Names: | ADP-ribosyltransferase C2 and C3 toxin-like 1; ARTC1; Mono(ADP-ribosyl)transferase 1; CD_antigen: CD296 |
| Protein Family: | Arrestin family protein |
| UniProt Gene Name: | ART1 |
| UniProt Entry Name: | NAR1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ART1 antibody (CAB10103) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human lung cancer using ART1 antibody (CAB10103) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of L929 cells using ART1 antibody (CAB10103) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of U-2 OS cells using ART1 antibody (CAB10103) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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