Anti-ANKS1B 항체 (CAB7820)

Antibody Name:	Anti-ANKS1B Antibody
Antibody SKU:	CAB7820
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 261-510 of human ANKS1B (NP_858056.2).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:	A-549, Mouse liver

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 261-510 of human ANKS1B (NP_858056.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	GFPF SAIH QVHN TGDW GEPS ITLR PPNE ATAS TPVQ YWQH HPEK LIFQ SCDY KAFY LGSM LIKE LRGT ESTQ DACA KMRA NCQK STEQ MKKV PTII LSVS YKGV KFID ATNK NIIA EHEI RNIS CAAQ DPED LSTF AYIT KDLK SNHH YCHV FTAF DVNL AYEI ILTL GQAF EVAY QLAL QARK GGHS STLP ESFE NKPS KPIP KPRV SIRK SVQI DPSE QKTL ANLP WIVE PGQE AKRG INTK YETT IF
Gene ID:	56899
Uniprot:	Q7Z6G8
Cellular Location:	Cajal body, Cell junction, Cell projection, Cytoplasm, Nucleus, dendritic spine, postsynaptic cell membrane, postsynaptic density, synapse
Calculated MW:	28kDa/40-57kDa/85kDa/138kDa
Observed MW:	80kDa

Synonyms:

ANKS1B, AIDA, AIDA-1, ANKS2, EB-1, EB1, cajalin-2

Background:

This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene.

UniProt Protein Function:	AIDA-1b: Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells. 8 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Cell adhesion Chromosomal Location of Human Ortholog: 12q23.1 Molecular Function:ephrin receptor binding
NCBI Summary:	This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]
UniProt Code:	Q7Z6G8
NCBI GenInfo Identifier:	332278155
NCBI Gene ID:	56899
NCBI Accession:	Q7Z6G8.2
UniProt Secondary Accession:	Q7Z6G8,Q5XLJ0, Q6IVB5, A5PKY5, A7E259, A8K153, A8MSN4 B4DFP6, B4DH98, F8VPM3, F8VZR9, F8WC27,
UniProt Related Accession:	Q7Z6G8
Molecular Weight:	44,522 Da
NCBI Full Name:	Ankyrin repeat and sterile alpha motif domain-containing protein 1B
NCBI Synonym Full Names:	ankyrin repeat and sterile alpha motif domain containing 1B
NCBI Official Symbol:	ANKS1B
NCBI Official Synonym Symbols:	EB1; AIDA; EB-1; ANKS2; AIDA-1; cajalin-2
NCBI Protein Information:	ankyrin repeat and sterile alpha motif domain-containing protein 1B
UniProt Protein Name:	Ankyrin repeat and sterile alpha motif domain-containing protein 1B
UniProt Synonym Protein Names:	Amyloid-beta protein intracellular domain-associated protein 1; AIDA-1; E2A-PBX1-associated protein; EB-1
Protein Family:	Ankyrin repeat and sterile alpha motif domain-containing protein
UniProt Gene Name:	ANKS1B
UniProt Entry Name:	ANS1B_HUMAN

Western blot analysis of extracts of various cell lines, using ANKS1B antibody (CAB7820) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)