Anti-ALDH1L2 Antibody (CAB14455)
- SKU:
- CAB14455
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-ALDH1L2 Antibody |
| Antibody SKU: | CAB14455 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human ALDH1L2 (NP_001029345.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse pancreas, Rat pancreas, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human ALDH1L2 (NP_001029345.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EPLE IKGA KKPG LVTK NGLV LFGN DGKA LTVR NLQF EDGK MIPA SQYF STGE TSVV ELTA EEVK VAET IKVI WAGI LSNV PIIE DSTD FFKS GASS MDVA RLVE EIRQ KCGG LQLQ NEDV YMAT KFEG FIQK VVRK LRGE DQEV ELVV DYIS KEVN EIMV KMPY QCFI NGQF TDAD DGKT YDTI NPTD GSTI CKVS YASL A |
| Gene ID: | 160428 |
| Uniprot: | Q3SY69 |
| Cellular Location: | Mitochondrion |
| Calculated MW: | 22kDa/57kDa/101kDa |
| Observed MW: | 102KDa |
| Synonyms: | ALDH1L2, mtFDH |
| Background: | This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | ALDH1L2: a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010] |
| UniProt Protein Details: | Protein type:EC 1.5.1.6; Oxidoreductase Chromosomal Location of Human Ortholog: 12q23.3 Cellular Component: mitochondrion Molecular Function:4-trimethylammoniobutyraldehyde dehydrogenase activity; aminobutyraldehyde dehydrogenase activity; formyltetrahydrofolate dehydrogenase activity; hydroxymethyl-, formyl- and related transferase activity; methyltransferase activity Biological Process: 10-formyltetrahydrofolate catabolic process; biosynthetic process; methylation; one-carbon compound metabolic process |
| NCBI Summary: | This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010] |
| UniProt Code: | Q3SY69 |
| NCBI GenInfo Identifier: | 238814322 |
| NCBI Gene ID: | 160428 |
| NCBI Accession: | NP_001029345.2 |
| UniProt Secondary Accession: | Q3SY69,Q3SY68, Q68D62, Q6AI55, Q8N922, |
| UniProt Related Accession: | Q3SY69 |
| Molecular Weight: | 57,244 Da |
| NCBI Full Name: | mitochondrial 10-formyltetrahydrofolate dehydrogenase |
| NCBI Synonym Full Names: | aldehyde dehydrogenase 1 family member L2 |
| NCBI Official Symbol: | ALDH1L2 |
| NCBI Official Synonym Symbols: | mtFDH |
| NCBI Protein Information: | mitochondrial 10-formyltetrahydrofolate dehydrogenase |
| UniProt Protein Name: | Mitochondrial 10-formyltetrahydrofolate dehydrogenase |
| UniProt Synonym Protein Names: | Aldehyde dehydrogenase family 1 member L2 |
| Protein Family: | Mitochondrial 10-formyltetrahydrofolate dehydrogenase |
| UniProt Gene Name: | ALDH1L2 |
| UniProt Entry Name: | AL1L2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ALDH1L2 antibody (CAB14455) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
Anti-SLC20A2 Antibody (CAB6739)
Anti-CHRDL1 Antibody (CAB15204)
