UniProt Protein Function: | AIDA-1b: Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells. 8 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell adhesion Chromosomal Location of Human Ortholog: 12q23.1 Molecular Function:ephrin receptor binding |
NCBI Summary: | This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011] |
UniProt Code: | Q7Z6G8 |
NCBI GenInfo Identifier: | 332278155 |
NCBI Gene ID: | 56899 |
NCBI Accession: | Q7Z6G8.2 |
UniProt Secondary Accession: | Q7Z6G8,Q5XLJ0, Q6IVB5, A5PKY5, A7E259, A8K153, A8MSN4 B4DFP6, B4DH98, F8VPM3, F8VZR9, F8WC27, |
UniProt Related Accession: | Q7Z6G8 |
Molecular Weight: | 44,522 Da |
NCBI Full Name: | Ankyrin repeat and sterile alpha motif domain-containing protein 1B |
NCBI Synonym Full Names: | ankyrin repeat and sterile alpha motif domain containing 1B |
NCBI Official Symbol: | ANKS1B |
NCBI Official Synonym Symbols: | EB1; AIDA; EB-1; ANKS2; AIDA-1; cajalin-2 |
NCBI Protein Information: | ankyrin repeat and sterile alpha motif domain-containing protein 1B |
UniProt Protein Name: | Ankyrin repeat and sterile alpha motif domain-containing protein 1B |
UniProt Synonym Protein Names: | Amyloid-beta protein intracellular domain-associated protein 1; AIDA-1; E2A-PBX1-associated protein; EB-1 |
Protein Family: | Ankyrin repeat and sterile alpha motif domain-containing protein |
UniProt Gene Name: | ANKS1B |
UniProt Entry Name: | ANS1B_HUMAN |