UniProt Protein Function: | ANKK1: belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009] |
UniProt Protein Details: | Protein type:Protein kinase, TKL; Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); TKL group; RIPK family Chromosomal Location of Human Ortholog: 11q23.2 Molecular Function:protein serine/threonine kinase activity; ATP binding Biological Process: protein amino acid phosphorylation |
NCBI Summary: | The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009] |
UniProt Code: | Q8NFD2 |
NCBI GenInfo Identifier: | 30425444 |
NCBI Gene ID: | 255239 |
NCBI Accession: | NP_848605.1 |
UniProt Related Accession: | Q8NFD2 |
Molecular Weight: | 84,632 Da |
NCBI Full Name: | ankyrin repeat and protein kinase domain-containing protein 1 |
NCBI Synonym Full Names: | ankyrin repeat and kinase domain containing 1 |
NCBI Official Symbol: | ANKK1 |
NCBI Official Synonym Symbols: | PKK2 |
NCBI Protein Information: | ankyrin repeat and protein kinase domain-containing protein 1; sgK288; X-kinase; sugen kinase 288; protein kinase PKK2 |
UniProt Protein Name: | Ankyrin repeat and protein kinase domain-containing protein 1 |
UniProt Synonym Protein Names: | Protein kinase PKK2; Sugen kinase 288; SgK288; X-kinase |
Protein Family: | Ankyrin repeat and protein kinase domain-containing protein |
UniProt Gene Name: | ANKK1 |
UniProt Entry Name: | ANKK1_HUMAN |