AMPD2 Antibody (PACO22139)
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주문- SKU:
- PACO22139
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AMPD2 Antibody (PACO22139) |
Antibody SKU: | PACO22139 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human AMPD2. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from HeLa cells, NIH-3T3 cells and COLO205 cells, using AMPD2 antibody. |
Background: | AMP deaminase plays a critical role in energy metabolism. |
Synonyms: | AMD2; AMP deaminase 2; AMP deaminase isoform L; |
UniProt Protein Function: | AMPD2: AMP deaminase plays a critical role in energy metabolism. Belongs to the adenosine and AMP deaminases family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Hydrolase; EC 3.5.4.6; Nucleotide Metabolism - purine Chromosomal Location of Human Ortholog: 1p13.3 Cellular Component: cytosol Molecular Function:AMP deaminase activity; protein binding Biological Process: IMP biosynthetic process; purine salvage Disease: Pontocerebellar Hypoplasia, Type 9; Spastic Paraplegia 63, Autosomal Recessive |
NCBI Summary: | The protein encoded by this gene is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
UniProt Code: | Q01433 |
NCBI GenInfo Identifier: | 12644375 |
NCBI Gene ID: | 271 |
NCBI Accession: | Q01433.2 |
UniProt Secondary Accession: | Q01433,Q14856, Q14857, Q16686, Q16687, Q16688, Q16729 Q5T693, Q5T695, B4DK50, B4DZI5, E9PNG0, |
UniProt Related Accession: | Q01433 |
Molecular Weight: | 88,288 Da |
NCBI Full Name: | AMP deaminase 2 |
NCBI Synonym Full Names: | adenosine monophosphate deaminase 2 |
NCBI Official Symbol: | AMPD2 |
NCBI Official Synonym Symbols: | PCH9; SPG63 |
NCBI Protein Information: | AMP deaminase 2 |
UniProt Protein Name: | AMP deaminase 2 |
UniProt Synonym Protein Names: | AMP deaminase isoform L |
Protein Family: | AMP deaminase |
UniProt Gene Name: | AMPD2 |
UniProt Entry Name: | AMPD2_HUMAN |