AKR7A3 Antibody (PACO43705)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO43705
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AKR7A3 Antibody (PACO43705) |
Antibody SKU: | PACO43705 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Aflatoxin B1 aldehyde reductase member 3 protein (1-331AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human liver tissue using PACO43705 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO43705 at dilution of 1:100. |
Background: | Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. |
Synonyms: | Aflatoxin B1 aldehyde reductase member 3 (EC 1) (AFB1 aldehyde reductase 2) (AFB1-AR 2), AKR7A3, AFAR2 |
UniProt Protein Function: | AKR7A3: Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily. |
UniProt Protein Details: | Protein type:Oxidoreductase; EC 1.-.-.- Chromosomal Location of Human Ortholog: 1p36.13 Cellular Component: cytosol Molecular Function:aldo-keto reductase activity; electron carrier activity; protein binding Biological Process: aldehyde metabolic process; xenobiotic metabolic process |
NCBI Summary: | Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004] |
UniProt Code: | O95154 |
NCBI GenInfo Identifier: | 13123960 |
NCBI Gene ID: | 22977 |
NCBI Accession: | O95154.2 |
UniProt Secondary Accession: | O95154,Q86SR4, Q8IVN6, Q8N5V6, Q8TAX1, Q9NUC3, |
UniProt Related Accession: | O95154 |
Molecular Weight: | 37,206 Da |
NCBI Full Name: | Aflatoxin B1 aldehyde reductase member 3 |
NCBI Synonym Full Names: | aldo-keto reductase family 7 member A3 |
NCBI Official Symbol: | AKR7A3 |
NCBI Official Synonym Symbols: | AFAR2 |
NCBI Protein Information: | aflatoxin B1 aldehyde reductase member 3 |
UniProt Protein Name: | Aflatoxin B1 aldehyde reductase member 3 |
UniProt Synonym Protein Names: | AFB1 aldehyde reductase 2; AFB1-AR 2 |
Protein Family: | Aflatoxin B1 aldehyde reductase |
UniProt Gene Name: | AKR7A3 |
UniProt Entry Name: | ARK73_HUMAN |