AGPAT3 Antibody (PACO22079)
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주문- SKU:
- PACO22079
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AGPAT3 Antibody (PACO22079) |
Antibody SKU: | PACO22079 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human AGPAT3. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from K562 cells, using AGPAT3 antibody. |
Background: | Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA. |
Synonyms: | 1-acylglycerol-3-phosphate o-acyltransferase 3; agpat3; agpat3 protein; lpaat-gamma1; lysophosphatidic acid acyltransferase-gamma1 |
UniProt Protein Function: | AGPAT3: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Membrane protein, multi-pass; Membrane protein, integral; EC 2.3.1.51; Lipid Metabolism - glycerolipid; Acetyltransferase Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; Golgi membrane; membrane; plasma membrane Molecular Function:1-acylglycerol-3-phosphate O-acyltransferase activity Biological Process: phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process |
NCBI Summary: | The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NRZ7 |
NCBI GenInfo Identifier: | 12643817 |
NCBI Gene ID: | 56894 |
NCBI Accession: | Q9NRZ7.1 |
UniProt Secondary Accession: | Q9NRZ7,Q3ZCU2, Q6UWP6, Q6ZUC6, Q8N3Q7, Q9NRZ6, D3DSL2 |
UniProt Related Accession: | Q9NRZ7 |
Molecular Weight: | 45,514 Da |
NCBI Full Name: | 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma |
NCBI Synonym Full Names: | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
NCBI Official Symbol: | AGPAT3 |
NCBI Official Synonym Symbols: | LPAAT3; LPAAT-GAMMA1 |
NCBI Protein Information: | 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma |
UniProt Protein Name: | 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma |
UniProt Synonym Protein Names: | 1-acylglycerol-3-phosphate O-acyltransferase 3; 1-AGP acyltransferase 3; 1-AGPAT 3; Lysophosphatidic acid acyltransferase gamma; LPAAT-gamma |
Protein Family: | 1-acyl-sn-glycerol-3-phosphate acyltransferase |
UniProt Gene Name: | AGPAT3 |
UniProt Entry Name: | PLCC_HUMAN |